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Electrochemically Induced, Metal Free Synthesis of 2-substituted chroman-4-ones. | LitMetric

Electrochemically Induced, Metal Free Synthesis of 2-substituted chroman-4-ones.

ChemistryOpen

Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924, Łódź, Poland.

Published: November 2024

Electrochemically induced, decarboxylative functionalization of chromone-3-carboxylic acids by N-hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on the direct reduction of NHPI esters using electric current. Developed protocol provides a straightforward route to the synthesis of diverse molecules with potential biological activity.

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Source
http://dx.doi.org/10.1002/open.202400395DOI Listing

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