AI Article Synopsis
- * The majority (about 85%) of anal cancers are squamous cell carcinomas and are linked to human papillomavirus (HPV).
- * There is a noted need for more effective primary prevention strategies to address the rising incidence of anal cancer, as indicated by national data trends.
Article Abstract
Anal cancer is a rare disease, accounting for only 2% of all gastrointestinal tract malignancies. While individuals with advanced age (>50 years) and female sex have an increased risk of anal cancer, there has been a trend toward diagnosis at a younger age particularly among men who have sex with men, irrespective of their human immunodeficiency virus status. Histologically, approximately 85% of anal cancers are squamous cell carcinomas (ASCC). However, while more than 90% of ASCC is associated with oncogenic human papillomavirus, the temporal trends of anal cancer incidence modeled on national databases represent an unmet need for primary prevention.
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| http://dx.doi.org/10.1016/j.soc.2024.07.011 | DOI Listing |
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