SnapShot: Targeted protein degradation.

Cell

State Key Laboratory of Medical Neurobiology, Neurology Department at Huashan Hospital, School of Life Sciences, Fudan University, Shanghai 200433, China. Electronic address:

Published: November 2024

Targeted protein degradation strategies leverage endogenous cellular degradation machinery to selectively eliminate a protein of interest. Emerging technologies are opening avenues in drug discovery and functional characterization of intracellular, membrane, and extracellular proteins. To view this SnapShot, open or download the PDF.

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Source
http://dx.doi.org/10.1016/j.cell.2024.10.025DOI Listing

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