High-intensity neutron beams, such as those available at the European Spallation Source (ESS), provide new opportunities for fundamental discoveries. Here, we discuss a novel Ramsey neutron-beam experiment to search for ultralight axion dark matter through its coupling to neutron spins, which would cause the neutron spins to rotate about the velocity of the neutrons relative to the dark matter halo. We estimate that experiments at the HIBEAM beamline with a 50 m free flight path at the ESS can improve the sensitivity to the axion-neutron coupling compared to the current best laboratory limits by up to 2-3 orders of magnitude over the axion mass range 10^{-22} eV-10^{-16} eV.
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http://dx.doi.org/10.1103/PhysRevLett.133.181001 | DOI Listing |
Sci Total Environ
December 2024
State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China.
Nanoplastics (NPs) have been found in natural environments. However, the sequestration of NPs and natural organic matter (NOM) coupled with the Fe(III) hydrolysis and subsequent iron oxides transformation remains unclear. Here, we investigated the behaviors of NPs during the dynamic transformation process of iron oxides in the presence of humic acids (HA).
View Article and Find Full Text PDFSci Rep
December 2024
Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Falmouth, USA.
Coral reef sponges efficiently take up particulate and dissolved organic matter (DOM) from the water column and release compounds such as nucleosides, amino acids, and other dissolved metabolites to the surrounding reef via their exhalent seawater, but the influence of this process on reef picoplankton and nutrient processing is relatively unexplored. Here we examined the impact of sponge exhalent on the reef picoplankon community and subsequent alterations to the reef dissolved metabolite pool. We exposed reef picoplankton communities to a sponge exhalent water mixture (Niphates digitalis and Xestospongia muta) or filtered reef seawater (control) in closed, container-based dark incubations.
View Article and Find Full Text PDFActa Neurol Belg
December 2024
Lamezia Terme Hospital, Catanzaro, Italy.
Curr Issues Mol Biol
December 2024
Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Canine mammary carcinomas (CMCs) represent the most prevalent form of cancer in female dogs, characterized by a high incidence and mortality rate. C6 ceramide is recognized for its multifaceted anti-cancer properties, yet its specific influence on CMCs remains to be elucidated. Long noncoding RNAs (lncRNAs), now recognized as functional "dark matter" in precision oncology, are particularly intriguing, with 44% of canine lncRNAs exhibiting tissue-specific expression.
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemical Sciences and Center for Advanced Functional Materials, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, West Bengal, India.
Triple-negative breast cancer (TNBC) poses significant treatment challenges due to its high metastasis, heterogeneity, and poor biomarker expression. The N-terminus of an octapeptide NAPVSIPQ () was covalently coupled to a carboxylic acid derivative of Ru(2,2'-bipy) () to synthesize an N-stapled short peptide-Rubpy conjugate (). This photosensitizer (PS) was utilized to treat TNBC through microtubule (MT) targeted chemotherapy and photodynamic therapy (PDT).
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