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The challenge of preventing gastric cancer in patients under surveillance for familial adenomatous polyposis.
Fam Cancer
January 2025
Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Several extra-colonic manifestations, including duodenal polyposis and desmoid tumors, are well-described manifestations in familial adenomatous polyposis (FAP). More recently, an increase in gastric cancer diagnoses has been observed in FAP. This case series presents nine patients with FAP who were diagnosed with gastric cancer at our FAP expertise center, of whom eight were diagnosed between 2017 and 2023, while before 2017 the only diagnosis of gastric cancer was in 2001.
View Article and Find Full Text PDFDesmoid fibromatosis post-cervical spine surgical intervention.
BJR Case Rep
January 2025
Dubai Health, Dubai 1853, United Arab Emirates.
Article Synopsis
- Desmoid tumours are rare benign growths that can aggressively invade surrounding tissues, especially near nerves and blood vessels, making them difficult to treat.
- Their exact cause is unknown, but they are more common in females and may be linked to factors like trauma, surgery, or inflammation, suggesting possible genetic or hormonal influences.
- A case study highlights a 34-year-old woman who developed a desmoid tumour in her neck after neck surgery; despite surgical removal, the tumour recurred, necessitating a second operation for complete treatment.
Familial adenomatous polyposis family with clustering of psychiatric disorders.
Jpn J Clin Oncol
January 2025
Department of Clinical Oncology, Graduate School of Medicine, Akita University, Hondo 1-1-1, Akita, 010-8543, Japan.
Article Synopsis
- Familial adenomatous polyposis (FAP) is an inherited disorder caused by mutations in the APC gene, leading to colorectal polyps and other health issues.
- This condition can also cause extracolonic manifestations like desmoid tumors and various mental disorders in affected families.
- A case study highlights the importance of mental health care in genetic counseling, as a family with FAP showed connections between the disorder and mental health issues, including autism spectrum disorder and intellectual disabilities.
Breast Desmoid Tumours: A Review of the Literature.
Breast J
January 2025
Australian National University School of Medicine and Psychology, Canberra, ACT 2600, Australia.
Breast desmoid tumour is a rare type of benign breast disease that presents like malignancy. Current guidelines are based on limited evidence derived from case reports and small case series and recommend resection with microscopically-negative margin (R0). There is a high risk of recurrence despite negative surgical margins.
View Article and Find Full Text PDFDesmoid-type fibromatosis of the breast in a male patient following cosmetic surgery: a rare case report.
Front Oncol
December 2024
Angeles Breast Center, Hospital Ángeles Valle Oriente, San Pedro Garza Garcia, Nuevo Leon, Mexico.
Background: Desmoid-type fibromatosis of the breast is a rare, benign, but locally aggressive tumor that typically affects women. Its presentation in male patients is exceedingly rare, and even more so following a cosmetic procedure such as liposuction. This case report describes a unique presentation of breast fibromatosis in a male patient, who developed the condition after undergoing liposuction for cosmetic purposes to define the pectoral area.
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