Background: Male breast cancer is a very rare disease and only accounts for around 1% of all breast cancers. The treatment strategies are based on those used for breast cancer in women. So far, there is a lack of randomized data to support specific treatment modalities in men. To our knowledge, a therapeutic approach with a combination of letrozole and abemaciclib has not yet been described for a male patient with metastatic breast cancer.

Case Description: Here, we report a case of a male patient with advanced metastatic breast cancer treated with a combination of letrozole and abemaciclib. The therapy was well tolerated with no reported side effects. The follow-up CT showed regression of the primary tumor mass and the lymph nodes and soft tissue metastases.

Conclusion: In summary, this case report clearly shows the effectiveness of the therapeutic approach and should be discussed for the treatment of future patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564860PMC
http://dx.doi.org/10.1002/cnr2.70054DOI Listing

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