Background: Total knee arthroplasty (TKA) is a widely performed procedure that significantly enhances patients' quality of life by reducing pain and improving daily function. While the traditional tibial plate design used in TKA has been symmetrical, there has been a recent trend towards using asymmetrical designs. Our study aimed to compare symmetrical and asymmetrical tibial designs, focusing on outcomes related to overhang, malrotation, and tibial coverage.
Methods: This systematic review was conducted in accordance with PRISMA guidelines. A comprehensive search of PubMed, Scopus, Web of Science, and Cochrane databases was carried out up to January 22nd, 2024, to identify comparative studies on symmetrical and asymmetrical designs, as well as those reporting postoperative functional and clinical outcomes. The risk of bias in the included studies was evaluated using the Newcastle-Ottawa Scale (NOS).
Results: This systematic review included 587 patients from seven comparative studies that met the inclusion criteria. Our findings indicate that asymmetrical tibial components generally provided better outcomes in terms of tibial coverage, malrotation, and overhang. Asymmetrical designs provided greater tibial coverage and reduced posterolateral overhang compared to symmetrical designs, which is essential for minimizing complications like soft tissue irritation and patellar maltracking. Additionally, asymmetrical components were associated with less severe tibial malrotation.
Conclusion: This systematic review showed that asymmetrical tibial implants offer better tibial coverage, with less overhang and fewer rotational issues compared to symmetrical implants. As a result, asymmetrical designs in TKA may lower complication rates, enhance patient satisfaction, and improve quality of life post-surgery.
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http://dx.doi.org/10.1186/s13018-024-05256-z | DOI Listing |
Trials were inconsistent while reporting findings on the benefits of the intermittent regimen. Recent conclusive evidence to show overall effect was limited. This review compared intermittent and daily iron folic acid supplementation (IFAS) on pregnancy outcomes.
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January 2025
Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Background: Oral infectious diseases, such as dental caries, periodontitis and periapical periodontitis, are often complicated by causative bacterial biofilm formation and significantly impact human oral health and quality of life. Bacteriophage (phage) therapy has emerged as a potential alternative with successful applications in antimicrobial trials. While therapeutic use of phages has been considered as effective treatment of some infectious diseases, related research focusing on oral infectious diseases is few and lacks attention.
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Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, Tamil Nadu, India.
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View Article and Find Full Text PDFJ Orthop Surg Res
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Sichuan University, Chengdu, Sichuan Province, 610041, People's Republic of China.
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