Karl Ziegler is considered one of the most outstanding chemists of the 20th century. In particular, his work on organometallic mixed catalysts, which allows the polymerization of ethylene at normal pressure, led to a revolution in plastics production and changed the everyday life of all mankind. In 1963, he was awarded the Nobel Prize in Chemistry for this work, together with Giulio Natta. This article focuses on Ziegler's early career, which has received little attention to date. It describes his youth and study years in Marburg, which partly coincide with the First World War. Subsequently, his postdoctoral period is examined, which led him via Marburg and Frankfurt to his first associate professorship in Heidelberg. Special attention is paid to his relationship to National Socialism, which he opposed. As a result, Ziegler experienced professional difficulties in the 1930s, such as repeated rejection when filling various professorships. His appointment as a full professor in Halle and his subsequent directorship at the Max-Planck-Institut für Kohlenforschung (Coal Research), where he finally achieved his greatest research achievement, are described in the following.
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http://dx.doi.org/10.1002/anie.202403180 | DOI Listing |
Mol Biol Cell
June 2024
Department of Physics and Astronomy, Purdue University, West Lafayette, IN 47907.
Microfluidic platforms enable long-term quantification of stochastic behaviors of individual bacterial cells under precisely controlled growth conditions. Yet, quantitative comparisons of physiological parameters and cell behaviors of different microorganisms in different experimental and device modalities is not available due to experiment-specific details affecting cell physiology. To rigorously assess the effects of mechanical confinement, we designed, engineered, and performed side-by-side experiments under otherwise identical conditions in the Mother Machine (with confinement) and the SChemostat (without confinement), using the latter as the ideal comparator.
View Article and Find Full Text PDFMAGMA
October 2021
Department of Cardiology, Academic Teaching Hospital Agatharied of the Ludwig-Maximilians-University Munich, Agatharied, Germany.
Objective: Image post-processing corrects for cardiac and respiratory motion (MoCo) during cardiovascular magnetic resonance (CMR) stress perfusion. The study analyzed its influence on visual image evaluation.
Materials And Methods: Sixty-two patients with (suspected) coronary artery disease underwent a standard CMR stress perfusion exam during free-breathing.
Biomed Opt Express
January 2020
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Fluorescence nanoscopy has become an indispensable tool for studying organelle structures, protein dynamics, and interactions in biological sciences. Single-molecule localization microscopy can now routinely achieve 10-50 nm resolution through fluorescently labeled specimens in lateral optical sections. However, visualizing structures organized along the axial direction demands scanning and imaging each of the lateral imaging planes with fine intervals throughout the whole cell.
View Article and Find Full Text PDFMicrobiology (Reading)
March 2016
Institut für Biologie, Humboldt-Universität zu Berlin, Chausseestraße 117, 10115 Berlin, Germany.
Most cyanobacteria use a single type of cyanophycin synthetase, CphA1, to synthesize the nitrogen-rich polymer cyanophycin. The genomes of many N2-fixing cyanobacteria contain an additional gene that encodes a second type of cyanophycin synthetase, CphA2. The potential function of this enzyme has been debated due to its reduced size and the lack of one of the two ATP-binding sites that are present in CphA1.
View Article and Find Full Text PDFPlant Biotechnol J
May 2008
Agrobiotechnology, University of Rostock, Justus-von-Liebig-Weg 8, 18059 Rostock, Germany.
The production of biodegradable polymers in transgenic plants is an important challenge in plant biotechnology; nevertheless, it is often accompanied by reduced plant fitness. In order to decrease the phenotypic abnormalities caused by cytosolic production of the biodegradable polymer cyanophycin, and to increase polymer accumulation, four translocation pathway signal sequences for import into chloroplasts were individually fused to the coding region of the cyanophycin synthetase gene (cphA(Te)) of Thermosynechococcus elongatus BP-1, resulting in the constructs pRieske-cphA(Te), pCP24-cphA(Te), pFNR-cphA(Te) and pPsbY-cphA(Te). These constructs were expressed in Nicotiana tabacum var.
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