Objectives: Current literature links substance abuse with primary emotions and dissociative symptoms, but little research combines these relationships. This study investigates the clinical significance of these concepts and the mediating role of dissociative symptoms in the relationship between primary emotions and substance abuse.
Methods: Study 1 included 517 adults (77.6 % female, Age: M = 27.84) from the community. Path analysis examined the relationships between primary emotions (BANPS-GL), dissociative symptoms (FDS), psychopathology (BSI-18), and substance abuse (WHO-ASSIST). Study 2 involved 73 inpatients with substance use disorders (SUD) compared to 73 matched individuals from the general population, totalling 146 participants (21.9 % female, Age: M = 34.90). MANOVA and Discriminant analysis assessed the differences and contributions of the variables to group separation.
Results: Significant correlations were found between the FDS and the WHO-ASSIST, all BSI-scales, and all primary emotions except SEEKING. The FDS was a key mediator between primary emotions and substance abuse (WHO-ASSIST) and effectively differentiated between the clinical and general population groups.
Conclusions: These findings highlight the role of dissociative symptoms in the relationship between emotional experiences and addictive behaviour. Future research should consider dissociative symptoms in the prevention and treatment of addictive disorders.
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http://dx.doi.org/10.1016/j.jad.2024.11.031 | DOI Listing |
Cell Rep
December 2024
Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai 200040, China. Electronic address:
Dissociation, characterized by altered consciousness and perception, underlies multiple mental disorders, but the specific neuronal subtypes involved remain elusive. In mice, we find that dissociation-inducing doses of ketamine significantly inhibit retrosplenial cortex (RSC) parvalbumin interneurons (PV-INs), enhancing delta oscillations (1-3 Hz) and delta-gamma phase-amplitude coupling (δ-γ PAC) and inducing dissociation-like behaviors. Optogenetic inhibition of RSC PV-INs triggers delta oscillations, δ-γ PAC, and some dissociation-like behaviors without ketamine.
View Article and Find Full Text PDFAnn Gen Psychiatry
December 2024
Faculty of Medicine, Department of Psychiatry, Karadeniz Technical University, 61080, Trabzon, Türkiye.
Background: Dissociative amnesia, a disorder characterized by impairments in multiple memory areas, is frequently associated with trauma. Complex post-traumatic stress disorder (CPTSD) is marked by mood dysregulation, negative self-concept, and impaired interpersonal relationships, in addition to the classic symptoms of post-traumatic stress disorder (PTSD). The relationship between CPTSD and dissociative amnesia, as well as whether CPTSD should be considered a dissociative subtype, remains uncertain in the literature.
View Article and Find Full Text PDFJ Parasitol
December 2024
Water, Sanitation and Hygiene Research and Development Centre, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Many technical aspects are associated with helminth egg isolation and enumeration that affect how efficiently eggs are recovered from samples. This study investigated Ascaris egg recoverability when samples were washed with or without pressure, and from different sample types (water, effluent, ventilated improved pit latrine [VIP], urine diversion dry toilet [UDDT], dried, fatty, and septic tank sludges, and soil) when processed with water, ammonium bicarbonate, and 7X®. We also looked at egg recovery after flotation with zinc sulfate, magnesium sulfate, and sodium nitrate at specific gravities of 1.
View Article and Find Full Text PDFJ Dermatol
December 2024
Department of Psychiatry, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.
Although genetic, environmental, autoimmune, and psychological factors are believed to play a role in the onset of alopecia areata (AA), the exact cause remains unknown. This study aimed to investigate whether there are differences in traumatic experiences, dissociative symptoms, and alexithymia levels between groups. Fifty eight patients diagnosed with AA, 58 individuals with dermatological diseases thought to have a low psychosomatic component, and 58 individuals not diagnosed with any chronic disease were included in the study.
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