Prostate Cancer is a disease that affects the male reproductive system. The irregularity of the symptoms makes it hard for the clinicians to pinpoint the disease in the earlier stages. Techniques such as Machine Learning, Data Science, Deep Learning, etc. have been employed on the biomedical data to identify the symptoms of the patients and predict their stage and the chances of their survival. The survival analysis of prostate cancer is essential as it guides the clinicians to recommend the optimal treatment for the patient. Building an accurate model from electronic data using machine learning is quite difficult. This review article presents a systematic literature review focused on the area of prostate cancer survival analysis utilizing machine learning and other soft computing techniques. Through an extensive evaluation of the available research, we have identified and summarized key insights from the selected studies. A comprehensive comparison of various approaches for survival and treatment predictions in the literature has been conducted. Additionally, the gaps in previous research have been discussed, highlighting areas for further investigation and providing future recommendations. By synthesizing the current knowledge in prostate cancer survival analysis, this review contributes to the understanding of the field and lays the foundation for future advancements.
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http://dx.doi.org/10.1016/j.prp.2024.155687 | DOI Listing |
Prostate Cancer
December 2024
Department of Histopathology and Cytology, Faculty of Medical Laboratory Sciences, Al-Neelain University, Khartoum, Sudan.
Prostate cancer is the most common noncutaneous malignancy among men worldwide, including in Sudan, where it represents a significant public health challenge. CD147, a transmembrane glycoprotein implicated in tumor progression, invasion, and metastasis, has shown potential as a prognostic biomarker in various cancers. This retrospective case-control study aimed to evaluate CD147 expression in prostate adenocarcinoma among Sudanese men and its association with tumor grade.
View Article and Find Full Text PDFJ West Afr Coll Surg
August 2024
Division of Urology, Department of Surgery, College of Health Sciences, University of Abuja, Abuja, Nigeria.
Background: Prostate cancer (PCa) was the most common noncutaneous cancer among Nigerian men in 2020. Despite this high incidence, documented rates may be an underestimation.
Objectives: This study aimed to determine the hospital incidence rate, trends, and characterise the clinicopathologic features, and treatment outcomes of patients with PCa in our institution.
Oncol Res
December 2024
Department of Rehabilitation, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China.
Background: Transmembrane emp24 trafficking protein 3 (TMED3) is associated with the development of several tumors; however, whether TMED3 regulates the progression of prostate cancer remains unclear.
Materials And Methods: Short hairpin RNA was performed to repress TMED3 in prostate cancer cells (DU145 cells) and in a prostate cancer mice model to determine its function in prostate cancer and .
Results: In the present study, we found that TMED3 was highly expressed in prostate cancer cells.
Front Oncol
December 2024
Department of Orthopedics, Chengdu Fifth People's Hospital, Chengdu, China.
Background: Prostate cancer (PCa) ranks as the second leading cause of cancer-related mortality among men. Long non-coding RNAs (lncRNAs) are known to play a regulatory role in the development of various human cancers. LncRNA MAFG-divergent transcript (MAFG-DT) was reported to play a crucial role in tumor progression of multiple human cancers, such as pancreatic cancer, colorectal cancer, bladder cancer, and gastric cancer.
View Article and Find Full Text PDFBioinform Adv
November 2024
Laboratory of Molecular Science and Engineering, Åbo Akademi University, Henrikinkatu 2, Turku 20500, Finland.
Motivation: NMR-based metabolomics is a field driven by technological advancements, necessitating the use of advanced preprocessing tools. Despite this need, there is a remarkable scarcity of comprehensive and user-friendly preprocessing tools in Python. To bridge this gap, we have developed Protomix-a Python package designed for metabolomics research.
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