PtosisDiffusion: a training-free workflow for precisely predicting post-operative appearance in blepharoptosis patients based on diffusion models.

Front Cell Dev Biol

Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases, Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, Zhejiang, China.

Published: October 2024

Purpose: This study aims to develop a diffusion-based workflow to precisely predict postoperative appearance in blepharoptosis patients.

Methods: We developed PtosisDiffusion, a training-free workflow that combines face mesh with ControlNet for accurate post-operative predictions, and evaluated it using 39 preoperative photos from blepharoptosis patients. The performance of PtosisDiffusion was compared against three other diffusion-based methods: Conditional Diffusion, Repaint, and Dragon Diffusion.

Results: PtosisDiffusion demonstrated superior performance in subjective evaluations, including overall rating, correction, and double eyelid formation. Statistical analyses confirmed that PtosisDiffusion achieved the highest overlap ratio (0.87 0.07) and an MPLPD ratio close to 1 (1.01 0.10). The model also showed robustness in extreme cases, and ablation studies confirmed the necessity of each model component.

Conclusion: PtosisDiffusion generates accurate postoperative appearance predictions for ptosis patients using only preoperative photographs. Among the four models tested, PtosisDiffusion consistently outperformed the others in both subjective and statistical evaluation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557522PMC
http://dx.doi.org/10.3389/fcell.2024.1459336DOI Listing

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