AI Article Synopsis

  • Neurologic symptoms can sometimes signal celiac disease (CD), and two children with ocular paroxysmal non-epileptic events (PNEEs) were diagnosed with CD.
  • A review of 12 patients showed that 25% were also diagnosed with CD after presenting with similar symptoms.
  • Screening for CD in patients displaying PNEEs may be beneficial in order to avoid unnecessary testing and to quickly implement a gluten-free diet, potentially improving their condition.

Article Abstract

Introduction: Neurologic manifestations may be presenting signs of celiac disease (CD). Pediatric-onset paroxysmal non-epileptic events (PNEEs) are not included among them.

Cases Presentation: We report the case of two children who presented with ocular PNEEs in association with mild symptoms evocative for CD, who were subsequently diagnosed with CD and experienced regression of PNEEs on a gluten-free diet. Data from 12 patients undergoing neurological evaluation in 2019-2023 for ocular PNEEs were reviewed: 3 (25%) had a subsequent diagnosis of CD.

Conclusions: Ocular PNEEs could be a presenting manifestation of CD. In the diagnostic work-up of PNEEs, screening for CD could be included, both to avoid unnecessary tests and to promptly start a gluten-free diet, which might lead to a favorable clinical response.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557330PMC
http://dx.doi.org/10.3389/fped.2024.1450563DOI Listing

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