This study aimed to assess the effectiveness of photobiomodulation therapy (PBM) and leukocyte plasma-rich fibrin (L-PRF) in enhancing or accelerating osseointegration by promoting dental implant stability. The study included 15 patients lacking posterior mandibular teeth. Each participant received two implants in the mandibular edentulous area at the lower posterior region. The implants on the right side were categorized into three groups: Group A (650 nm laser), Group B (976 nm laser), and Group C with L-PRF (10 implants each). The left side served as the control. L-PRF was applied at the implant base before placement. Laser irradiation was performed on the buccal and lingual sides of the implants. Osseointegration was assessed using the AnyCheck system from Neo-Biotic Company. The Implant Stability Quotient (ISQ), ranging from 0-100, was measured post-operatively and after three months. There was a significant increase in stability after three months, particularly with 650 nm laser photobiomodulation followed by L-PRF application. The differences in ISQ among the three groups were statistically significant. After three months, implant stability was significantly higher both buccally and lingually in Group A, using powers of 75 mW and 100 mW, respectively, compared to the control ( <0.01). These findings indicate that PBM and L-PRF can significantly enhance osseointegration and improve dental implant stability in the posterior mandible. Patients and clinicians should consider the potential benefits of these interventions in implant dentistry, especially in cases involving the posterior mandible, where stability is crucial for successful implant outcomes.
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http://dx.doi.org/10.25122/jml-2023-0281 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Division of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Background: Despite advancements in prosthetic designs and surgical techniques, patellar dislocation remains a rare but significant complication following total knee arthroplasty, with an incidence ranging between 0.15% and 0.5%.
View Article and Find Full Text PDFDrug Resist Updat
December 2024
Department of General Surgery, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China. Electronic address:
The balance between CD8 T cells and regulatory T (Treg) cells in the tumor microenvironment (TME) plays a crucial role in the immune checkpoint inhibition (ICI) therapy in gastric carcinoma (GC). However, related factors leading to the disturbance of TME and resistance to ICI therapy remain unknown. In this study, we applied N6-methyladenosine (m6A) small RNA Epitranscriptomic Microarray and screened out 3'tRF-AlaAGC based on its highest differential expression level and lowest inter-group variance.
View Article and Find Full Text PDFACS Nano
January 2025
School of Mechanical and Manufacturing Engineering, University of New South Wales, Sydney, New South Wales 2052, Australia.
Implantable systems with chronic stability, high sensing performance, and extensive spatial-temporal resolution are a growing focus for monitoring and treating several diseases such as epilepsy, Parkinson's disease, chronic pain, and cardiac arrhythmias. These systems demand exceptional bendability, scalable size, durable electrode materials, and well-encapsulated metal interconnects. However, existing chronic implantable bioelectronic systems largely rely on materials prone to corrosion in biofluids, such as silicon nanomembranes or metals.
View Article and Find Full Text PDFJ Mol Cell Biol
January 2025
Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, College of Life Science, Northeast Agricultural University, Harbin 150030, China.
The zygotic genome activation (ZGA) is crucial for the development of pre-implantation embryos. Long noncoding RNAs (lncRNAs) play significant roles in many biological processes, but the study on their role in the early embryonic development of pigs is limited. In this study, we identify lncFKBPL as an enhancer-type lncRNA essential for pig embryo development.
View Article and Find Full Text PDFCureus
December 2024
Trauma and Orthopaedics, PSG Institute of Medical Sciences and Research, Coimbatore, IND.
Background Numerous classifications exist for intertrochanteric (IT) fractures, commonly focused on stability. However, the currently utilized Arbeitsgemeinschaft Osteosynthesefragen and Orthopaedic Trauma Association (AO/OTA) classification has limitations in identifying irreducible fractures. This study aims to answer the following questions: does fracture stability imply irreducibility; which fracture fragments complicate reduction; and which reduction techniques should be employed? Materials and methods Eligibility criteria included fractures in adult long bones without pathological fractures being treated by native conservative means.
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