Large-aperture elements would induce unnegligible systematic errors due to material inhomogeneity, manufacturing or gravity, that are difficult to correct in an extreme large aperture flat interferometer and result in reference wavefront distortion. We propose an active-compensation method for systematic errors by employing a deformable mirror into the interferometer to modulate reference wavefront. A mapping relationship between sag of the deformable mirror and reference wavefront error is derived by theory of matrix optics, and two interferometer optical paths are designed for whether the deformable mirror is located at the pupil or not. The algorithm for calculating and controlling the sag of a deformable mirror can eliminate the need for the deformable mirror to be positioned at the pupil in order to achieve controllable modulation of the wavefront. This algorithm has been validated through the intentional introduction of systematic errors into the 1000 mm aperture flat interferometer for effective compensation. Moreover, the optimization algorithm in Ansys Zemax is utilized to calculate the optimal solution for surface shape of the deformable mirror, treating it as a nominal value. The algorithm error is on the order of 10 mm, falling within the acceptable tolerance range for the deformable mirror's surface shape.
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Proc Natl Acad Sci U S A
January 2025
Shenzhen Key Laboratory of Biomolecular Assembling and Regulation, Department of Neuroscience, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.
Ankyrin Repeat Domain-containing Protein 11 () is a causative gene for KBG syndrome, a significant risk factor for Cornelia de Lange syndrome (CdLS), and a highly confident autism spectrum disorder gene. Mutations of lead to developmental abnormalities in multiple organs/tissues including the brain, craniofacial and skeletal bones, and tooth structures with unknown mechanism(s). Here, we find that ANKRD11, via a short peptide fragment in its N-terminal region, binds to the cohesin complex with a high affinity, implicating why mutation can cause CdLS.
View Article and Find Full Text PDFSoft Matter
January 2025
Department of Materials Science, University of Patras, 26504 Patras, Greece.
Monte Carlo molecular simulations of curve-shaped rods show the propensity of such shapes to polymorphism revealing both smectic and polar nematic phases. The nematic exhibits a nanoscale modulated local structure characterized by a unique, polar, -symmetry axis that tightly spirals generating a mirror-symmetry-breaking organization of the achiral rods-form chirality. A comprehensive characterization of the polarity and its symmetries in the nematic phase confirms that the nanoscale modulation is distinct from the elastic deformations of a uniaxial nematic director in the twist-bend nematic phase.
View Article and Find Full Text PDFRev Sci Instrum
January 2025
State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.
Atom interferometry shows high sensitivity for inertial measurements in the laboratory, but it faces difficulties in field applications because of a trade-off between sensitivity and size. Therefore, there is an urgent need to develop a small sensor with high resolution for measuring acceleration and rotation in inertial navigation applications. Presented here is a miniaturized inertial sensor capable of measuring acceleration and rotation simultaneously based on high-resolution dual atom interferometers.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Advanced Radiology Services, P.C., Grand Rapids, Michigan.
"Situs inversus with levocardia" refers to the mirror-image lateral orientation of the abdominal organs with a normally oriented, left-sided heart. This anatomical anomaly arises from abnormalities in the biochemical signaling systems mediating embryological development. We present a case of situs inversus with levocardia incidentally discovered in a healthy 24-year-old male during workup following a motor vehicle collision.
View Article and Find Full Text PDFTaiwan J Obstet Gynecol
January 2025
Department of Obstetrics and Gynecology, Changhua Christan Hospital, Changhua, Taiwan. Electronic address:
Objective: Prenatal diagnosis of fetal 13q34 microdeletion is a rare condition, which may present with abnormal fetal development, including facial dysmorphism, mental retardation, and developmental delay. We present a pregnant woman in whom the fetus presented with a 0.24-cm ventricular septal defect at 20 weeks of gestation, with fetal 13q34 (113610612-115092648) deletion.
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