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http://dx.doi.org/10.1016/j.asjsur.2024.10.186 | DOI Listing |
Alzheimers Dement
December 2024
McGill University, Montreal, QC, Canada.
Background: Activation of the mTOR pathway is pivotal for microglia to induce and sustain neuroprotective functions (Ulland et al., 2017; Wang et al., 2022).
View Article and Find Full Text PDFCureus
December 2024
Radiology, Hospital Regional Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Monterrey, MEX.
Splenic artery pseudoaneurysms represent one of the most feared vascular complications of chronic pancreatitis. Sectional imaging studies such as computed tomography represent the first-line diagnostic tool for this pathology, being found as an incidental finding in patients with risk factors. We report the case of a splenic artery pseudoaneurysm in a 55-year-old patient diagnosed with chronic pancreatitis.
View Article and Find Full Text PDFInt J Nanomedicine
January 2025
Digestive Endoscopy Center, Department of Spleen and Gastroenterology, Yunnan Provincial Hospital of Traditional Chinese Medicine, Kunming, 650021, People's Republic of China.
Globally, wound care has become a significant burden on public health, with annual medical costs reaching billions of dollars, particularly for the long-term treatment of chronic wounds. Traditional treatments, such as gauze and bandages, often fail to provide an ideal healing environment due to their lack of effective biological activity. Consequently, researchers have increasingly focused on developing new dressings.
View Article and Find Full Text PDFAnticancer Res
January 2025
Department of Surgery, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
Background/aim: Liver metastasis (LM), pre-dominant in pancreatic cancer, is associated with a dismal 5-year survival rate. Reports on the presence of fatty liver and liver fibrosis in LM are conflicting. Although liver biopsy is the standard diagnostic method for fibrosis, alternative, less invasive scoring models have been explored.
View Article and Find Full Text PDFPhytomedicine
December 2024
Institue of Pharmaceutical Department, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, No 117, Meishan Road, Hefei 230031, Anhui, PR China. Electronic address:
Background: Xiaohua Funing Tang (XHFND) is a decoction formula of traditional Chinese medicine (TCM) and possesses the potential to manage chronic atrophic gastritis (CAG) with liver depression and spleen deficiency (LDSD), but the mechanisms were still unclear.
Purpose: Our aim is to reveal the overall synergistic mechanisms of XHFND against CAG with LDSD.
Methods: Based on a CAG rat model with LDSD, this study combined metabolomics, gut microbiota, and network pharmacology techniques to demonstrate the XHFND mechanisms with multiple components and targets.
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