The Role of Nuclear Medicine in Imaging and Therapy of Prostate Cancer: The State of the Art.

Urol Clin North Am

Department of Nuclear Medicine, Sheba Medical Center, Tel-Hashomer, 31 Emek Ha'ela Street, Ramat Gan 52621, Israel; Faculty of Medicine, Tel Aviv University, 35 klachkin Street, Tel Aviv 69978, Israel.

Published: February 2025

Prostate cancer (PCa) is the second most diagnosed cancer in men. In recent years, nuclear medicine has played an expanding role in diagnosing, staging, monitoring, and treating PCa. Specifically, the introduction of prostate-specific membrane antigen PET/computed tomography has significantly contributed to detecting locoregional and distant disease. Radioligand therapy, with its capacity to induce highly selective cytotoxic effects, is progressively being integrated into PCa therapy. The advent of novel therapeutic agents, additional indications, and a more comprehensive integration between nuclear imaging and therapy, represent the forefront of nuclear medicine in PCa.

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http://dx.doi.org/10.1016/j.ucl.2024.07.004DOI Listing

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