Early-Onset Trajectories of Emotional Dysregulation in Autistic Children.

Objective: Emotional dysregulation (ED) is a common and debilitating problem for autistic children and their families. However, little is known about early-onset patterns of dysregulation, associated risk factors, and child and family outcomes. This study aimed to characterize trajectories of ED in an inception cohort of autistic preschoolers.

Method: Caregivers reported on ED of 396 autistic children using the Aberrant Behavior Checklist Irritability and Hyperactivity/Noncompliance subscales at 6 time points from shortly after autism spectrum disorder diagnosis (ages 2-4 years) to preadolescence (ages 10-11 years). Covariance pattern mixture modeling was used to characterize the number and shape of latent dysregulation trajectories that best fit underlying data. Child and family correlates were measured at baseline and between ages 10 and 11 years to characterize early risk factors and preadolescent profiles associated with distinct latent trajectories.

Results: Three distinct trajectory classes best fit the data: persistently self-regulated (18% of sample), moderate and declining (54%), and persistently dysregulated (28%). Children classified in the persistently dysregulated trajectory lived with more depressed caregivers and in families reporting greater relationship problems and lower household incomes compared with children in lower-risk trajectories. Few associations were found with baseline child characteristics. Persistent dysregulation problems were associated with significantly worse child mental health and functional outcomes during preadolescent years.

Conclusion: Risk of persistent severe ED may be identifiable at the time of early autism diagnosis. Diagnostic assessments should include contextual risk factors and links to evidence-based family supports and interventions.