Objective: Adolescents with disrupted rest-activity rhythms (RARs), including shorter sleep duration, later sleep timing, and low physical activity levels, are at greater risk for mental health and behavioral problems. It remains unclear whether the same associations can be observed for within-subject changes in RARs.
Method: This longitudinal investigation on RARs used Fitbit data from the Adolescent Brain Cognitive Development (ABCD) Study at the 2-year follow-up (FL2) (ages 10-13 years) and 4-year follow-up (FL4) (ages 13-16 years). Good-quality Fitbit data were available for 963 youths at both time points. Changes in RARs from FL2 to FL4, their environmental and demographic contributors, and brain and behavioral correlates were examined.
Results: From FL2 to FL4, adolescents showed decreases in sleep duration and physical activity as well as delayed sleep timing (Cohen d = 0.44-0.75). Contributions of environmental and demographic factors to RAR changes were greatest for sleep timing (explained 10% variance) and least for sleep duration (explained 1% variance). Delays in sleep timing had stronger correlations with behavioral problems including impulsivity and poor academic performance than reductions in sleep duration or physical activity. Additionally, the various brain measures differed in their sensitivity to RAR changes. Reductions in sleep duration were associated with decreased functional connectivity between subcortical regions and sensorimotor and cingulo-opercular networks and with enhanced functional connectivity between sensorimotor, visual, and auditory networks. Delays in sleep timing were mainly associated with gray matter changes in subcortical regions.
Conclusion: The current findings corroborate the importance of sleep and physical activity in brain neurodevelopment and behavioral problems in adolescents. RARs might serve as biomarkers for monitoring behavioral problems and be potential therapeutic targets for mental disorders in adolescents.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jaac.2024.11.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Engagement in moderate-intensity physical activity supports overnight memory retention in older adults.
Sci Rep
December 2024
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA, 92697, USA.
Preserving the ability to vividly recall emotionally rich experiences contributes to quality of life in older adulthood. While prior works suggest that moderate-intensity physical activity (MPA) may bolster memory, it is unclear whether this extends to emotionally salient memories consolidated during sleep. In the current study, older adults (mean age = 72.
View Article and Find Full Text PDFCross sectional associations of physical activity and sleep with mental health among Chinese university students.
Sci Rep
December 2024
School of Physical Education, Shanghai University of Sport, Shanghai, 200438, China.
Objective: This study aimed to examine the levels of physical activity (PA), sleep, and mental health (MH), specifically depression, anxiety, and stress, among Chinese university students. It also aimed to analyze the influencing factors of MH, providing a theoretical foundation for developing intervention programs to improve college students' mental health.
Methods: A stratified, clustered, and phased sampling method was employed.
Efficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy.
J Pain Res
December 2024
Department of Pain Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, People's Republic of China.
Background: The best tool for the management of pain associated with distal symmetric peripheral neuropathy (DSPN) is a matter of debate. Therefore, the study aimed to explore whether ultrasound-guided pulsed radiofrequency (PRF) therapy of the stellate ganglion (SG) in type 2 diabetes mellitus (T2DM) patients with painful DSPN could decrease pain severity and the need for analgesics.
Methods: Fifty-six T2DM patients with refractory painful DSPN were enrolled in this study, who then received bilateral ultrasound-guided PRF therapy of SG.
The relationship between adolescent sleep duration and exposure to school bullying: the masking effect of depressive symptoms.
Front Psychol
December 2024
Key Laboratory of Xinjiang Endemic and Ethnic Diseases of the Ministry of Education, Department of Public Health, Shihezi University School of Medicine, Xinjiang, China.
Background: Adolescents who suffer from school bullying are often accompanied by problems such as sleep disorders and depression. However, it remains unclear how depressive symptoms and sleep assessments such as sleep duration interact in the specific mechanisms of exposure to school bullying.
Objective: To understand the role of sleep duration, depressive symptoms on school bullying in adolescents and the mediating role of sleep duration in this context.
Orthologs of and impact sleep in mice.
Sleep Adv
December 2024
Murine Phenotyping Core, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Model organisms such as are powerful tools to study the genetic basis of sleep. Previously, we identified the genes and using selective breeding for long and short sleep duration in an outbred population of . is a transcription factor that is part of the epidermal growth factor receptor signaling pathway, while is involved in proline and arginine metabolism.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!