Objectives: To propose and validate a minimally invasive combined static and dynamic computer assisted implant surgery (CAIS) workflow for zygomatic implant (ZI) placement.
Methods: A combined approach leveraging static CAIS for initial positioning, complemented by dynamic CAIS for real-time control of the angle, depth and width was proposed. Fourteen consecutive patients (age: 60.3±9.8 years; 8 females) seeking ZI-supported restoration were enrolled. A single anatomically and prosthetically driven ZI on either the unilateral zygoma or bilateral zygomata was planned and placed using the proposed approach. The zygomatic anatomy-guided approach (ZAGA) type and the ZI length were recorded. The angular, coronal global, and apical global deviation between the planned and placed positions were measured by overlapping post- and pre-operative cone beam computer tomography. Comparisons were made between the left and right sides across the ZAGA type and ZI length. Statistical significance was set at P<0.05.
Results: 22 ZIs were placed using the combined approach and 13 immediate loading prostheses were delivered, with one patient restored 6 months after surgery. The angular deviations and coronal global deviations were 1.99±0.17° and 1.21±0.45 mm, respectively. The median apical global deviation was 1.67 mm (interquartile range [IQR]: 1.11-1.93 mm). No significant differences were found between the left and right sides across the ZAGA type or ZI length. All ZIs remained stable over a median follow-up of 14.5 months (IQR: 7-20 months).
Conclusions: The proposed combination of static and dynamic CAIS is safe, reliable, accurate, and robust for ZI placement.
Clinical Significance: This pilot study proposed a minimally invasive ZI placement method that combined static and dynamic computer-guided surgery. The implant positioning accuracy achieved using this approach validated its safety, reliability, accuracy, and robustness. The combined approach may reduce the technique sensitivity of ZI placement, facilitating future rehabilitation of severely atrophic or defective maxillae.
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http://dx.doi.org/10.1016/j.jdent.2024.105453 | DOI Listing |
J Prosthet Dent
January 2025
Professor, Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianopolis, SC, Brazil.
Statement Of Problem: Digital surgical guides improve precision by detailing the direction, position, and angle of implants, which reduces surgery time and complications. A bibliometric analysis of guided surgery in implant dentistry is lacking.
Purpose: The aim of this metrics-based analysis was to analyze the trends and key characteristics of articles related to guided surgery in implant dentistry.
J Strength Cond Res
December 2024
Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Rome Open University, Rome, Italy; and.
Racil, G, Padulo, J, Trabelsi, Y, Frizziero, A, Russo, L, and Migliaccio, GM. Rhythmic exercises before basketball training: A study on motor skills, static balance, and reaction speed in school-aged children. J Strength Cond Res 38(12): e761-e768, 2024-The aim of this study was to investigate the effects of combining rhythmic exercises with basketball training on the improvement of basic motor and physical skills in children.
View Article and Find Full Text PDFSoft Matter
January 2025
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Microfluidic chips are powerful tools for investigating numerous variables including chemical and physical parameters on protein aggregation. This study investigated the aggregation of bovine serum albumin (BSA) in two different systems: a vial-based static system and a microfluidic chip-based dynamic system in which BSA aggregation was induced successfully. BSA aggregation induced in a microfluidic chip on a timescale of seconds enabled a dynamic investigation of the forces driving the aggregation process.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2024
Key Laboratory of Modern Preparations of Traditional Chinese Medicine, Ministry of Education, Jiangxi University of Chinese Medicine Nanchang 330004, China National Key Laboratory of Creation of Modern Chinese Medicine with Classical Formulas Nanchang 330004, China Jiangxi Technology Innovation Center of Green Manufacturing of Chinese Medicine Nanchang 330004, China.
The construction method and simulation parameter settings for the discrete element model of Jianwei Xiaoshi Granules, as the primary material of Jianwei Xiaoshi Tablets, are not yet clear. The accuracy of the simulation model significantly influences the dynamic response characteristics between granules. Therefore, it is necessary to calibrate the parameters to improve the accuracy of the simulation parameters.
View Article and Find Full Text PDFbioRxiv
January 2025
Ben-May Institute for Cancer Research, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA.
Insulin degrading enzyme (IDE) is a dimeric 110 kDa M16A zinc metalloprotease that degrades amyloidogenic peptides diverse in shape and sequence, including insulin, amylin, and amyloid-β, to prevent toxic amyloid fibril formation. IDE has a hollow catalytic chamber formed by four homologous subdomains organized into two ~55 kDa N- and C- domains (IDE-N and IDE-C, respectively), in which peptides bind, unfold, and are repositioned for proteolysis. IDE is known to transition between a closed state, poised for catalysis, and an open state, able to release cleavage products and bind new substrate.
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