Rheumatic fever (RF) remains a significant global health concern, particularly in regions with limited access to health care. Despite its association with group A streptococcal infections, diagnosing RF can be challenging because of its diverse clinical presentations, including cardiac manifestations such as heart block. We present the case of a 13-year-old boy initially misdiagnosed with appendicitis whose subsequent evaluation revealed acute RF (ARF) with associated cardiac complications, including Mobitz type II heart block. Comprehensive cardiac investigations confirmed the diagnosis, highlighting the importance of considering ARF in patients presenting with cardiac abnormalities. Early recognition and management of ARF are crucial, particularly in cases involving cardiac manifestations such as heart block. Favorable outcomes were observed with appropriate medical therapy, emphasizing the effectiveness of multidisciplinary management in preventing disease progression.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11551923PMC
http://dx.doi.org/10.1016/j.jaccas.2024.102632DOI Listing

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