AI Article Synopsis

  • Gastrointestinal disorders, both functional (FGID) and non-functional (non-FGID), are common and can be influenced by psychological and socio-cultural factors, especially stressful life events, which affect patients' quality of life (QOL).
  • The study involved 200 participants to compare QOL and stressful life events between FGID and non-FGID patients, revealing that FGID patients had significantly lower QOL scores and that stress contributed notably to QOL variance in non-FGID patients.
  • The findings underline the need for clinicians to consider psycho-social factors in patient care for gastrointestinal disorders, stressing the importance of understanding cultural differences in how stress affects these conditions.

Article Abstract

Background: Gastrointestinal disorders, both non-functional and functional, are prevalent among the general population, and understanding these in relation to psychological factors is crucial for clinicians to design effective management strategies. Psycho-social factors, including stressful life events, significantly impact disease outcomes and quality of life (QOL). Limited research has explored these factors in the context of functional gastrointestinal disorders (FGIDs) and non-functional gastrointestinal disorders (non-FGIDs), especially in culturally diverse populations.

Aim: To investigate the relationship between QOL and stressful life events in patients with FGID and non-FGID.

Materials And Methods: This study involved 200 participants diagnosed with FGID using ROME IV criteria and non-FGID clinically. The research utilized a socio-demographic questionnaire, the Psychological General Well-Being Index (QOL), and the Presumptive Stressful Life Events Scale (PSLES).

Results: Among FGID patients, functional dyspepsia was the common diagnosis, while erosive gastritis was more prevalent among non-FGID patients. A significant association in QOL was observed between FGID and non-FGID ( < 0.001), with FGID patients exhibiting lower scores. Overall, a mild negative correlation was found between QOL and PSLES (r = -0.20, = 0.003). Stressful life events contributed to 13% variance of QOL in non-FGID patients.

Conclusion: This study highlights the impact of stressful life events on QOL in both FGID and non-FGID patients. While FGID patients experienced poorer QOL, non-FGID also showed QOL reductions with recent life events. Understanding these associations can aid clinicians in comprehensive patient care, emphasizing the importance of addressing psycho-social factors alongside clinical symptoms. Cultural nuances influencing stress perception and its relation to gastrointestinal disorders merit further investigation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553618PMC
http://dx.doi.org/10.4103/ipj.ipj_341_23DOI Listing

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