Asymptomatic Testicular Tumor in Patient with Retroperitoneal Fibrosis as Manifestation of IgG4-related Disease Recurrence: A Case Report.

Isr Med Assoc J

Department of Internal Medicine E, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.

Published: November 2024

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Article Synopsis
  • The case report details a rare occurrence of a postpubertal-type teratoma in a 48-year-old male, which appeared as a late recurrence of a previously diagnosed seminoma following testicular surgery six years earlier.
  • Imaging tests showed a retroperitoneal tumor with unusual characteristics, leading to a biopsy that indicated a high-grade malignant tumor, prompting neoadjuvant chemotherapy that helped shrink the tumor before surgical removal.
  • Further analysis revealed that the original seminoma diagnosis overlooked a mixed germ cell tumor component, underscoring the need for comprehensive histological evaluations in testicular germ cell tumors to better inform prognosis and treatment options.
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