Advance of Circulating Tumor Cells in the Prognosis and Management of Endometrial Cancer.

Cancer Invest

Department of Obstetrics and Gynecology, the First Hospital of Lanzhou University, Key Laboratory of Gynecologic Oncology of Gansu Province, Lanzhou, Gansu, China.

Published: November 2024

AI Article Synopsis

  • - Endometrial cancer (EC) is a prevalent type of cancer in women, and its death rates have been rising over the last two decades.
  • - Research indicates that circulating tumor cells (CTCs) can provide valuable information for understanding and managing EC, potentially leading to better personalized treatment options.
  • - This review emphasizes the significance of CTCs and disseminated tumor cells (DTCs) in predicting EC outcomes and highlights the potential diagnostic role of tumor cells found in urine from EC patients.

Article Abstract

Endometrial cancer (EC) is a common gynecological malignancy and its mortality has been increasing in the last twenty years. A growing body of evidence suggests that circulating tumor cells (CTCs) may provide a more complete tumor profile, facilitate the understanding of the molecular mechanism and individual management of EC patients. In this review, we presented the presence and clinical applications of CTCs and disseminated tumor cells (DTCs) in EC, particularly for EC prognosis and management, also highlighted the diagnostic value of tumor cells in urine of EC patients, aim to help researchers better focus on their study in this field.

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Source
http://dx.doi.org/10.1080/07357907.2024.2422607DOI Listing

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