Discovery of the Novel HLA-DRB1*16:02:13 Allele, a Variant of HLA-DRB1*16, in a Taiwanese Individual.

HLA

Laboratory of Immunogenetics, Tzu Chi Cord Blood Bank, and Buddhist Tzu Chi Bone Marrow Donor Registry, Buddhist Tzu Chi Stem Cells Centre, Hualien Tzu Chi Hospital, Buddhist Tzu chi Medical Foundation, Hualien, Taiwan, Republic of China.

Published: November 2024

AI Article Synopsis

  • A single nucleotide change in the DNA sequence at codon 206 of the HLA-DRB1*16:02:01:01 gene creates a new variation called HLA-DRB1*16:02:13.
  • This alteration involves a substitution that can lead to different immune system responses.
  • Understanding this new allele can help in research related to diseases and immune system functions.

Article Abstract

One nucleotide substitution in codon 206 of HLA-DRB1*16:02:01:01 results in a novel allele, HLA-DRB1*16:02:13.

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Source
http://dx.doi.org/10.1111/tan.15751DOI Listing

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