AI Article Synopsis
- Xanthophylls lutein and zeaxanthin are carotenoids known for their antioxidant benefits and roles in preventing eye diseases.
- The study evaluated the antioxidant capabilities of extra virgin olive oil (EVOO) enriched with lutein and zeaxanthin, finding that these enriched oils increased circulatory levels and urinary antioxidant capacity in participants.
- The findings suggest that these enriched EVOOs could serve as effective antioxidant supplements that may help manage or prevent eye diseases.
Article Abstract
Xanthophylls lutein and zeaxanthin are carotenoids with important antioxidant capacities and relevant roles against the prevention of eye diseases. In this study a valorization of non-commercial spinach to obtain lutein and zeaxanthin as raw materials to develop nutraceuticals was carried out. Three oil matrixes were analyzed: extra virgin olive oil (EVOO), lutein and zeaxanthin enriched EVOO (EVOO+LZ), and EVOO enriched with 25 % of EVOO+LZ (namely EVOO+D) to evaluate their biological potential as antioxidants. Urinary antioxidant total capacity, and circulatory blood levels of lutein and zeaxanthin were determined (in vivo analysis). Also, a simulation of gastrointestinal simulation (in vitro analysis) was performed. The results showed an increase in the circulatory levels of lutein-zeaxanthin after the ingestion of EVOO+LZ during 45 and 60 days, and an increase in the urinary antioxidant levels after the intake of EVOO+LZ and EVOO+D. In vitro assay revealed that both xanthophylls showed bioavailability to be assimilated in the intestinal tract. Therefore, these EVOO enriched with lutein-zeaxanthin might be considered as powerful antioxidant tools with potential properties in the management/prevention of eye diseases.
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| http://dx.doi.org/10.1016/j.foodchem.2024.141811 | DOI Listing |
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