Changes Over Time in Short-Term Stroke Outcomes by Race-Ethnicity.

Neurology

From the Department of Epidemiology (L.D.L., E.C., M.K., M.A.S., L.B.M.), School of Public Health, and Stroke Program (L.D.L., D.L.B., D.B.Z., L.B.M.), University of Michigan, Ann Arbor.

Published: December 2024

Objectives: The objective of this study was to quantify trends (2008-2019) in stroke outcomes by race-ethnicity.

Methods: Patients with ischemic stroke from a population-based study were interviewed at 90 days to assess outcomes. Linear regression with multiple imputation and inverse probability weighting was used to model trends.

Results: The median age was 66 years (n = 1,449); 61% were Mexican American (MA). QOL remained stable with no race-ethnic difference in trends ( for time*race-ethnicity interaction = 0.81). Neurologic outcomes improved for MA ( < 0.01) but not non-Hispanic White (NHW) persons with stroke ( = 0.23) with no race-ethnic difference in trends ( for interaction = 0.23). For functional outcomes, trends were stable and then improved in MA persons with stroke ( for interaction = 0.01), whereas trends were stable in NHW persons with stroke ( = 0.52). For cognitive outcomes, there was little change in NHW persons with stroke ( = 0.50); in MA persons with stroke, there was improvement followed by decline and then improvement ( = 0.03). No race-ethnic differences in trends in functional ( for interaction = 0.51) or cognitive ( for interaction = 0.21) outcomes were noted.

Discussion: Outcome improvements were noted in MA but not NHW persons with stroke; race-ethnic differences were not present in 2019. Understanding factors contributing to favorable trends in MA persons may be informative for improving outcomes in all persons.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11551720PMC
http://dx.doi.org/10.1212/WNL.0000000000210033DOI Listing

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