AI Article Synopsis

  • - Herpes simplex virus types 1 and 2 are the most common sexually transmitted infections in women, particularly prevalent in developing countries, and can cause serious complications if contracted during the perinatal period, affecting both mother and child.
  • - The diagnosis of HSV infection can be complicated due to a range of symptoms, from asymptomatic cases to those with non-specific signs, making clinical suspicion vital in suspected cases.
  • - The case presented involves a mother who suffered from severe HSV type 2 infection leading to viral hepatitis and fetal death, emphasizing the need for awareness in febrile women showing systemic illness during the perinatal phase, even without skin lesions.

Article Abstract

Herpes simplex virus (HSV) types 1 and 2 produce the most common sexually transmitted infection in women, with a higher incidence reported in developing countries. When the first infection occurs during the perinatal period, it can spread, resulting in high morbidity and mortality of the mother and child, in addition to mainly neurological sequelae in the newborn. Despite having reliable laboratory tests, the diagnosis of herpes simplex virus infection in this population is complex since the clinical presentation ranges from asymptomatic or with non-specific symptoms without lesions on the skin or mucous membranes. For this reason, a high clinical suspicion is necessary. Here, we present the case of a mother with disseminated herpes simplex virus type 2 infection with viral hepatitis and fetal death, highlighting the importance of suspecting the diagnosis in febrile women with systemic compromise during the perinatal period, even in the absence of rash.

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Source
http://dx.doi.org/10.7705/biomedica.7362DOI Listing

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