Salmonella Presence and Risk Mitigation in Pet Foods: A Growing Challenge with Implications for Human Health.

Pet food is increasingly recognized as a significant vehicle for the transmission of foodborne pathogens to humans. The intimate association between pets and their owners, coupled with the rising trend of feeding pets raw and unprocessed foods, contributes substantially to this issue. Salmonella contamination in pet food can originate from raw materials and feed ingredients, the processing environment, and postprocessing handling and applications. The absence of standardized postprocessing pathogen mitigation steps in the production of dry kibble and treats, along with the lack of validated heat and chemical interventions in raw pet foods, renders pet food susceptible to contamination by pathogens such as Salmonella, Listeria, E. coli, etc. Pets can then serve as carriers of Salmonella, facilitating its transmission to pet owners. Since 1999, there have been over 117 recalls of pet foods due to Salmonella contamination in the United States, with 11 of these recalls linked to human outbreaks. Notably, 5 of the 11 human outbreaks involved multidrug-resistant Salmonella strains. Various antimicrobial interventions, including high-pressure processing, ozone, irradiation, chemical treatments such as organic acids and acidulants, plant-derived antimicrobials, and biological interventions such as bacteriophages, have proven effective against Salmonella in pet foods. This review aims to summarize the prevalence of Salmonella in different types of pet foods, identify common sources of contamination, outline reported outbreaks, and discuss control measures and the regulatory framework governing pet food safety.