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Rescue Pallidotomy for Chorea Paralytica.
Mov Disord Clin Pract
November 2024
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Off-time Treatment Options for Parkinson's Disease.
Neurol Ther
April 2023
Department of Clinical Pharmacology and Neurosciences, Toulouse Parkinson Expert Centre, Toulouse NeuroToul Center of Excellence in Neurodegeneration (COEN), French NS-Park/F-CRIN Network, University of Toulouse 3, CHU of Toulouse, INSERM, Toulouse, France.
Motor fluctuations (MF) are deemed by patients with Parkinson's disease (PD) as the most troublesome disease feature resulting from the increasing impairment in responsiveness to dopaminergic drug treatments. MF are characterized by the loss of a stable response to levodopa over the nychthemeron with the reappearance of motor (and non-motor) parkinsonian clinical signs at various moments during the day and night. They normally appear after a few years of levodopa treatment and with a variable, though overall increasing severity, over the disease course.
View Article and Find Full Text PDFRescue procedure for isolated dystonia after the secondary failure of globus pallidus internus deep brain stimulation.
Front Neurosci
August 2022
Department of Neurology & Institute of Neurology, Ruijin Hospital, Affiliated With Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Introduction: Globus pallidus internus (GPi) deep brain stimulation (DBS) is widely used in patients with dystonia. However, 10-20% of patients receive insufficient benefits. The objectives of this study are to evaluate the effectiveness of bilateral subthalamic nucleus (STN) DBS along with unilateral posteroventral pallidotomy (PVP) in patients with dystonia who experienced unsatisfactory GPi-DBS and to address the reported rescue procedures after suboptimal DBS or lesion surgery in dystonia patients.
View Article and Find Full Text PDFUnilateral pallidotomy as a potential rescue therapy for cervical dystonia after unsatisfactory selective peripheral denervation.
J Neurosurg Spine
November 2020
1Department of Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; and.
Objective: Selective peripheral denervation (SPD) is a widely accepted surgery for medically refractory cervical dystonia (CD), but when SPD has failed, the available approaches are limited. The authors investigated the results from a cohort of CD patients treated with unilateral pallidotomy after unsatisfactory SPD.
Methods: The authors retrospectively analyzed patients with primary CD who underwent unilateral pallidotomy after SPD between April 2007 and August 2019.
Rescue pallidotomy for dystonia through implanted deep brain stimulation electrode.
Surg Neurol Int
November 2016
UCL Institute of Neurology, Queen Square, London, UK.
Background: Some patients with deep brain stimulation (DBS), where removal of implants is indicated due to hardware related infections, are not candidates for later re-implantation. In these patients a rescue lesion through the DBS electrode has been suggested as an option. In this case report we present a patient where a pallidotomy was performed using the DBS electrode.
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