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| http://dx.doi.org/10.2147/JMDH.S504508 | DOI Listing |
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Adapting lateral stepping control to walk on winding paths.
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Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address:
Most often, gait biomechanics is studied during straight-ahead walking. However, real-life walking imposes various lateral maneuvers people must navigate. Such maneuvers challenge people's lateral balance and can induce falls.
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Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy.
Protein precipitation is widely used for sample preparation ahead of liquid chromatography. This step is required to analyze small molecules without the interference of proteins contained in the matrix. Organic solvents and acidic chemicals are the two most popular reagents used for this scope.
View Article and Find Full Text PDFMolecular dynamics in pharmaceutical nanotechnology: simulating interactions and advancing applications.
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Department of Pharmaceutics, ShriRam College of Pharmacy, Banmore, Morena, Madhya Pradesh, India.
Molecular Dynamics (MD) simulations are now widely utilized in pharmaceutical nanotechnology to gain deeper understanding of nanoscale processes imperative to drug design. This review has also detailed how MD simulation can be employed in the study of drug-nanocarrier interactions, controlling release of chemical compounds from drug delivery systems and increasing solubility and bioavailability of nanocarriers. Furthermore, MD contributes to examining the drug delivery systems, measuring the toxic effects, and determining biocompatibility of nanomedical systems.
View Article and Find Full Text PDFPoly-skilling and advanced practice roles in perioperative care: protocol for a realist synthesis of evidence.
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Faculty of Medical Sciences, University College London, London, UK.
Introduction: An ageing population and a workforce crisis have triggered an ambitious UK strategy for sustained delivery of healthcare. In perioperative care (the management of patients from contemplation of surgery until full recovery), it is recognised that interventions are needed to place the workforce on a more sustainable footing through cross-functionality and skill-shifting, namely with advanced practice roles. However, despite some reports and reviews in the literature, it is unclear how skills development efforts may potentially support workforce transformation for an effective and resilient perioperative care workforce.
View Article and Find Full Text PDFConcatenating Microbial, Enzymatic, and Organometallic Catalysis for Integrated Conversion of Renewable Carbon Sources.
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Institute of Bio- and Geosciences 1: Biotechnology (IBG-1), Forschungszentrum Jülich GmbH, Jülich, Nordrhein-Westfalen 52428, Germany.
The chemical industry can now seize the opportunity to improve the sustainability of its processes by replacing fossil carbon sources with renewable alternatives such as CO, biomass, and plastics, thereby thinking ahead and having a look into the future. For their conversion to intermediate and final products, different types of catalysts-microbial, enzymatic, and organometallic-can be applied. The first part of this review shows how these catalysts can work separately in parallel, each route with unique requirements and advantages.
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