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Predicting extubation failure in neonates: The role of lung ultrasound and corrected gestational age in safe weaning in the NICU.
Eur J Pediatr
January 2025
Hospital de Clinicas de Porto Alegre, Rua Silva Jardim 1155 # 701, Porto Alegre, RS, 90450-071, Brazil.
Unlabelled: To evaluate the accuracy of the lung ultrasound score (LUS) in predicting ventilatory weaning failure during neonatal hospitalization in the NICU and to identify factors associated with weaning failure, including corrected gestational age (CGA). This prospective, longitudinal, pragmatic and observational cohort study included neonates on mechanical ventilation for at least 48 h. The primary outcome was the accuracy of lung ultrasound in predicting 3-day weaning failure, with the ROC curve used to determine the best LUS cutoff (sensitivity and specificity).
View Article and Find Full Text PDFIntegrated care for multi-domain vulnerability during pregnancy: a retrospective cohort study.
Arch Womens Ment Health
January 2025
Erasmus MC - Sophia Children's Hospital, Department Obstetrics and Gynaecology, Division Obstetrics and Fetal Medicine, University Medical Centre Rotterdam, Dr. Molewaterplein 40, 3015 GD, Rotterdam, South Holland, The Netherlands.
Purpose: Psychosocial risk factors are frequently present in pregnant women and are associated with adverse maternal and neonatal outcomes. Professional guidelines recommend early detection of vulnerability and provision of multidisciplinary care, including an integrated care plan for pregnant women with social factors, such as residing in deprived areas, teenage pregnancy, and psychiatric illness. However, to date, such approach is impeded by lack of data on co-occurrence of vulnerability.
View Article and Find Full Text PDFSleep for infants after discharge from a neonatal ward: Expert- and parent endorsed strategies.
Pediatr Res
January 2025
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.
Background: This study aims to outline sleep strategies grounded in scientific research and endorsed by sleep experts, integrating parental input into the evaluation process, to assist parents in supporting infant sleep after discharge from a neonatal ward.
Methods: A Delphi method, consisting of three rounds, was employed. Sleep strategies based on scientific literature were presented to sleep experts and parents of infants discharged from a neonatal ward.
NeoScore: a new tool to assess technical and non-technical skills during neonatal resuscitation.
J Perinatol
January 2025
Department of Women's and Children's Health, Maternal-Fetal Medicine Unit, University of Padua School of Medicine, Padua, Italy.
Background: Training with high-technology manikins improves cardio-pulmonary resuscitation (CPR) skill retention, but a checklist to assess both technical and non-technical skills is lacking. This study aimed to develop a standardized checklist to evaluate healthcare's performance during simulated Neonatal Resuscitation Program (NRP) scenarios.
Materials And Methods: Twenty-two international neonatal resuscitation experts participated in a two-step modified Delphi process, rating each checklist item on a scale of 1-5 and providing feedback.
Novel Approach to Vascular Thymic Tissue Transplantation in Humans: A Case Report.
Transplant Proc
January 2025
Departamento de Imágenes Diagnósticas, Fundación Valle del Lili, Cali, Colombia.
Background: Vascular thymus transplantation has been explored in animal models but remains untested in humans. Current approaches to congenital athymia involve avascular transplantation of allogeneic thymic tissue, which may delay immune recovery. Building on animal studies, we propose revascularization of thymic tissue in a human model.
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