AI Article Synopsis
- The study aimed to analyze the differences in eye structure between patients with cataracts and Retinitis Pigmentosa (RP) compared to those with cataracts alone.
- Researchers conducted a matched case-control study involving 28 patients in each group, focusing on various ocular measurements like lens thickness and anterior chamber depth.
- Results indicated that cataracts in patients with RP were associated with changes such as a thicker lens and shallower anterior chamber, suggesting that RP may affect lens and eye morphology due to weakened support structures.
Article Abstract
Purpose: To investigate the anterior segment morphology in cataracts with Retinitis Pigmentosa (RP).
Setting: XXXX (anonymized for review) University Hospital.
Design: A retrospective matched case-control study.
Methods: The analysis included 28 eyes of 28 patients with cataracts and RP and 28 eyes of 28 patients with cataracts but without RP, matched for age and sex. Lens thickness, anterior lens curvature (Front R), posterior lens curvature, anterior chamber depth (ACD), anterior chamber width, central corneal thickness (CCT), white-to-white distance (WTW), corneal curvature, and axial length (AL) were compared between the groups. Data were obtained from preoperative evaluations conducted before cataract surgery. The same set of comparisons was also conducted for 18 eyes of 18 patients with cataracts and RP and 18 eyes of 18 patients with cataracts but without RP, matched for age, sex, and AL. Cases including missing data, categorized as Emery-Little classification grade 4 or above, or those with a history of acute angle closure were excluded.
Results: In the age- and sex-matched analysis, cataracts with RP showed significantly a thicker lens, steeper Front R, shallower ACD, thinner CCT, and shorter AL. In the analysis matched by age, sex, and AL, cataracts with RP had a thicker lens, steeper Front R, and larger WTW.
Conclusions: Cataracts with RP demonstrated centripetal swelling of the lens, centrifugal corneal thinning, and AL shortening. A decrease in tension between the lens and eyeball wall due to zonular weakness in the RP may lead to swelling of the lens and horizontal flattening of the eyeball.
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| http://dx.doi.org/10.1097/j.jcrs.0000000000001582 | DOI Listing |
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