AI Article Synopsis
- Many high-value molecules are made by multifunctional enzymes found in Actinobacteria, which produce reactive intermediates.
- This study focuses on an iterative polyketide synthase (iPKS) from the marine microorganism PR4.
- The iPKS can create long polyenes, reaching up to C22 nonaenes, indicating potential for new chemical and biological discoveries.
Article Abstract
Many reactive intermediates leading to high value molecules are biosynthesised by multifunctional enzymes in Actinobacteria. Herein we report the workings of a cryptic iterative polyketide synthase (iPKS) from the marine microorganism PR4. The iPKS generates extended polyenes up to C22 nonaenes, preluding novel chemistry and biology.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11563203 | PMC |
| http://dx.doi.org/10.1039/d4cc04963b | DOI Listing |
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