Endoscopic ultrasound (EUS) is vital for early pancreatic cancer diagnosis. Advances in artificial intelligence (AI), especially deep learning, have improved medical image analysis. We developed and validated the Modified Faster R-CNN (M-F-RCNN), an AI algorithm using EUS images to assist in diagnosing pancreatic cancer. We collected EUS images from 155 patients across three endoscopy centers from July 2022 to July 2023. M-F-RCNN development involved enhancing feature information through data preprocessing and utilizing an improved Faster R-CNN model to identify cancerous regions. Its diagnostic capabilities were validated against an external set of 1,000 EUS images. In addition, five EUS doctors participated in a study comparing the M-F-RCNN model's performance with that of human experts, assessing diagnostic skill improvements with AI assistance. Internally, the M-F-RCNN model surpassed traditional algorithms with an average precision of 97.35%, accuracy of 96.49%, and recall rate of 5.44%. In external validation, its sensitivity, specificity, and accuracy were 91.7%, 91.5%, and 91.6%, respectively, outperforming non-expert physicians. The model also significantly enhanced the diagnostic skills of doctors. The M-F-RCNN model shows exceptional performance in diagnosing pancreatic cancer via EUS images, greatly improving diagnostic accuracy and efficiency, thus enhancing physician proficiency and reducing diagnostic errors.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543282PMC
http://dx.doi.org/10.1055/a-2422-9214DOI Listing

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