AI Article Synopsis
- - The study examined the survival benefits of automated peritoneal dialysis (APD) compared to continuous ambulatory peritoneal dialysis (CAPD), focusing on the effects of using icodextrin, with 148 patients categorized into four groups based on their treatment type over one year.
- - Results indicated that the use of icodextrin in CAPD (CAPD+ET) had better patient survival rates than APD without icodextrin (APD-ET), although the differences were not statistically significant, particularly among non-diabetic patients.
- - The findings suggest that APD without icodextrin may lead to poorer patient and technique survival due to challenges in volume control, particularly highlighted by a higher edema index
Article Abstract
Background: There is no conclusive evidence regarding the survival benefits of automated peritoneal dialysis (APD) or the use of icodextrin. This study aimed to evaluate patient and technique survival among four groups divided based on peritoneal dialysis modality and icodextrin use over 1 year.
Methods: We specifically included patients who underwent a single peritoneal dialysis modality for at least 1 year during that period (n = 148). The participants were categorized into four groups for comparison: continuous ambulatory peritoneal dialysis (CAPD) without icodextrin (CAPD-ET, n = 39); CAPD with icodextrin (CAPD+ET, n = 35); APD without icodextrin (APD-ET, n = 40); and APD with icodextrin (APD+ET, n = 34).
Results: The CAPD+ET group had a higher patient survival rate than that of the APD-ET group and also had a higher technique survival trend than that of the APD-ET group, despite no statistical significance. In patients without diabetes mellitus (DM), the APD-ET group had a poorer patient survival trend than those of the APD+ET or CAPD+ET groups. In patients without DM, the APD+ET group had a higher technique survival than the APD-ET group. In addition, the APD+ET group showed a higher technique survival trend than did the CAPD-ET group, despite non-statistical significance. The edema index after 1 year of follow-up was higher in the APD-ET group than in the other groups.
Conclusion: The present study demonstrated that patients undergoing APD without icodextrin had poor patient and technique survival trends, which may be caused by poor volume control.
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| http://dx.doi.org/10.23876/j.krcp.24.017 | DOI Listing |
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