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Multiclass Steroid Profiling in Short-Finned Pilot Whale Blubber Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Rapid Commun Mass Spectrom
March 2025
Chemical Sciences Division, National Institute of Standards and Technology, Charleston, South Carolina, USA.
Rationale: Wildlife scientists are quantifying steroid hormones in a growing number of tissues and employing novel methods that must undergo validation before application. This study tested the accuracy and precision of liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for use on blubber samples from short-finned pilot whales (Globicephala macrorhynchus). We expanded upon a method for corticosteroid quantification by adding analytes and optimizing internal standard (IS) application.
View Article and Find Full Text PDFRunning-In Behavior and Failure Mechanism Between AgCuNi Alloy and Au-Electroplated Layer.
Sensors (Basel)
December 2024
State Key Laboratory of Tribology in Advanced Equipment, Tsinghua University, Beijing 100084, China.
To avoid wear and tear of the slip ring due to electrical corrosion, the slip ring needs to undergo the running-in process under atmospheric conditions without current after assembly. To address the urgent demand for long-service capability space conductive slip rings in the aerospace field, the running-in behavior and failure mechanism between the AgCuNi alloy and Au-electroplated layer are investigated using a ball-on-disc tribometer in this paper. The results show that the transfer film composed of Au plays an important role in modifying the friction during the sliding process.
View Article and Find Full Text PDFEvaluating the Biomechanical Effects and Real-World Usability of a Novel Ankle Exo for Runners.
J Biomech Eng
January 2025
Department of Mechanical Engineering, Vanderbilt University, 2201 West End Avenue, Nashville, TN, 37235.
Achilles tendon overuse injuries are common for long-distance runners. Ankle exos (exoskeletons and exosuits) are wearable devices that can reduce Achilles tendon loading and could potentially aid in the rehabilitation or prevention of these injuries by helping to mitigate and control tissue loading. However, most ankle exos are confined to controlled lab testing and are not practical to use in real-world running.
View Article and Find Full Text PDFInterventions for quitting vaping.
Cochrane Database Syst Rev
January 2025
Department of Health Promotion and Policy, University of Massachusetts, Amherst, MA, USA.
Rationale: There is limited guidance on the best ways to stop using nicotine-containing vapes (otherwise known as e-cigarettes) and ensure long-term abstinence, whilst minimising the risk of tobacco smoking and other unintended consequences. Treatments could include pharmacological interventions, behavioural interventions, or both.
Objectives: To conduct a living systematic review assessing the benefits and harms of interventions to help people stop vaping compared to each other or to placebo or no intervention.
Bridging the gap: Integrating cutting-edge techniques into biological imaging with deepImageJ.
Biol Imaging
November 2024
Bioengineering Department[CMT1], Universidad Carlos III de Madrid, Leganes, Spain.
This manuscript showcases the latest advancements in deepImageJ, a pivotal Fiji/ImageJ plugin for bioimage analysis in life sciences. The plugin, known for its user-friendly interface, facilitates the application of diverse pre-trained convolutional neural networks to custom data. The manuscript demonstrates several deepImageJ capabilities, particularly in deploying complex pipelines, three-dimensional (3D) image analysis, and processing large images.
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