A radioimmunoassay was used to study the effect of 26-day clinostatic hypokinesia on the level of sex hormones and cortisol in the peripheral blood plasma of 10 female papio hamadryas immobilized in different phases of the menstrual cycle. A significant decrease in the level of estradiol in the follicular phase and progesterone in the luteal phase was shown whereas the levels of cortisol and testosterone did not practically vary. Dependence of the adrenal gland reactivity to an acute immobilization stress on a cycle phase with minimal values in the luteal period was shown. It is assumed that the revealed imbalance of sex steroids was one of the reasons for disturbance of menstrual function found in hypokinesia of the females in both phases of the cycle.
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