Pneumonia is a dangerous disease that kills millions of children and elderly patients worldwide every year. The detection of pneumonia from a chest x-ray is perpetrated by expert radiologists. The chest x-ray is cheaper and is most often used to diagnose pneumonia. However, chest x-ray-based diagnosis requires expert radiologists which is time-consuming and laborious. Moreover, COVID-19 and pneumonia have similar symptoms which leads to false positives. Machine learning-based solutions have been proposed for the automatic prediction of pneumonia from chest X-rays, however, such approaches lack robustness and high accuracy due to data imbalance and generalization errors. This study focuses on elevating the performance of machine learning models by dealing with data imbalanced problems using data augmentation. Contrary to traditional machine learning models that required hand-crafted features, this study uses transfer learning for automatic feature extraction using Xception and VGG-16 to train classifiers like support vector machine, logistic regression, K nearest neighbor, stochastic gradient descent, extra tree classifier, and gradient boosting machine. Experiments involve the use of hand-crafted features, as well as, transfer learning-based feature extraction for pneumonia detection. Performance comparison using Xception and VGG-16 features suggest that transfer learning-based features tend to show better performance than hand-crafted features and an accuracy of 99.23% can be obtained for pneumonia using chest X-rays.
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http://dx.doi.org/10.3233/THC-230313 | DOI Listing |
PLoS One
December 2024
Faculty of Medicine, Department of Medical Biochemistry and Molecular Biology, Fayoum University, Fayoum, Egypt.
Background: The SARS-CoV-2 virus's frequent mutations have made disease control with vaccines and antiviral drugs difficult; as a result, there is a need for more effective coronavirus drugs. Therefore, detecting the expression of various diagnostic biomarkers, including ncRNA in SARS-CoV2, implies new therapeutic strategies for the disease.
Aim: Our study aimed to measure NEAT-1, miR-374b-5p, and IL6 in the serum of COVID-19 patients, demonstrating the correlation between target genes to explore the possible relationship between them.
PLoS One
December 2024
Chair of Biomedical Physics, Department of Physics & School of Natural Sciences, Technical University of Munich, Garching bei München, Germany.
Background: Dark-field radiography has been proven to be a promising tool for the assessment of various lung diseases.
Purpose: To evaluate the potential of dose reduction in dark-field chest radiography for the detection of the Coronavirus SARS-CoV-2 (COVID-19) pneumonia.
Materials And Methods: Patients aged at least 18 years with a medically indicated chest computed tomography scan (CT scan) were screened for participation in a prospective study between October 2018 and December 2020.
J Imaging
December 2024
Institute of Oceanic Engineering Research, University of Malaga, 29010 Malaga, Spain.
On 11 February 2020, the prevalent outbreak of COVID-19, a coronavirus illness, was declared a global pandemic. Since then, nearly seven million people have died and over 765 million confirmed cases of COVID-19 have been reported. The goal of this study is to develop a diagnostic tool for detecting COVID-19 infections more efficiently.
View Article and Find Full Text PDFDiseases
December 2024
Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita 879-5593, Japan.
The prevalence of bronchiectasis is increasing globally, and early detection using chest imaging has been encouraged to improve its prognosis. However, the sensitivity of a chest X-ray as a screening tool remains unclear. This study examined the chest X-ray features predictive of bronchiectasis.
View Article and Find Full Text PDFWorld J Clin Cases
December 2024
Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
This editorial explores the clinical implications of organizing pneumonia (OP) secondary to pulmonary tuberculosis, as presented in a recent case report. OP is a rare condition characterized by inflammation in the alveoli, which spreads to alveolar ducts and terminal bronchioles, usually after lung injuries caused by infections or other factors. OP is classified into cryptogenic (idiopathic) and secondary forms, the latter arising after infections, connective tissue diseases, tumors, or treatments like drugs and radiotherapy.
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