Using intelligent monitoring systems can potentially improve the identification and management of ventilator-associated events (VAEs). This single-center retrospective observational study evaluated the impact of implementing intelligent monitoring systems on the clinical outcomes of patients with VAEs in an ICU setting. An intelligent VAE monitoring system was integrated into electronic medical records to continuously collect patient data and alert attending physicians when a ventilated patient met the criteria for a ventilator-associated condition, which was defined as an increase of at least three cm HO in positive end expiratory pressure (PEEP), an increase of at least 0.20 in the fraction of inspired oxygen (FiO), or the FiO being over baseline for at least two consecutive days. This study covered two phases, consisting of before using the intelligent monitoring system (2021-2022) and during its use (2023-2024). The results showed that patients monitored with the intelligent system experienced earlier VAE detection (4.96 ± 1.86 vs. 7.77 ± 3.35 days, < 0.001), fewer ventilator-associated condition (VAC) occurrences, and a shorter total duration of VACs. Additionally, the system significantly reduced ventilator days, antibiotic use, and 14-day mortality. Intelligent monitoring systems enhance VAE management, improve clinical outcomes, and provide valuable insights into the future of critical care medicine.
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http://dx.doi.org/10.3390/jcm13216600 | DOI Listing |
Commun Med (Lond)
December 2024
Shanghai Jiao Tong University, Shanghai, China.
Background: Medical Visual Question Answering (MedVQA) enhances diagnostic accuracy and healthcare delivery by leveraging artificial intelligence to interpret medical images. This study aims to redefine MedVQA as a generation task that mirrors human-machine interaction and to develop a model capable of integrating complex visual and textual information.
Methods: We constructed a large-scale medical visual-question answering dataset, PMC-VQA, containing 227,000 VQA pairs across 149,000 images that span various modalities and diseases.
Background: Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also understudied. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to assess the burden of, and trends in, diarrhoeal diseases overall and attributable to 13 pathogens, as well as the contributions of associated risk factors, in children and adults in 204 countries and territories from 1990 to 2021.
View Article and Find Full Text PDFJ Chromatogr A
December 2024
Office of China National Narcotics Control Commission-China Pharmaceutical University Joint Laboratory on Key Technologies of Narcotics Control, Beijing 100193, PR China; Key Laboratory of Drug Monitoring and Control, Drug Intelligence and Forensic Center, Ministry of Public Security, PR China Beijing 100193, PR China. Electronic address:
Wastewater analysis technology has emerged as a promising tool for monitoring illicit drug consumption. However, the current reliance on the solid-phase extraction (SPE) pre-treatment method presents significant challenges for widespread adoption and high-throughput monitoring, as it consumes a large amount of time and labor as well as requires specialized instruments. This study has developed a direct injection (DI) technique for UPLC-MS/MS, enabling the detection of 77 compounds encompassing metabolites of human biomarkers, illicit drugs, and new psychoactive substances.
View Article and Find Full Text PDFBiosens Bioelectron
December 2024
Laboratory of Agricultural Information Intelligent Sensing, College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, PR China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, PR China. Electronic address:
Plant electrical signals serve as a medium for long-distance signal transmission and are intricately linked to plant stress responses. High-fidelity acquisition and analysis of plant electrophysiological signals contribute to early stress identification, thereby enhancing agricultural production efficiency. While traditional plant electrophysiology monitoring methods like gel electrodes can capture electrical signals on plant surfaces, which face limitations due to the plant cuticle barrier, impacting signal accuracy.
View Article and Find Full Text PDFBiosens Bioelectron
December 2024
Hubei University of Science & Technology, Xianning Medical College, Xianning, Hubei, 437100, China. Electronic address:
Scanning Electrochemical Probe Microscopy (SEPM) shows significant potential promise for analyzing localized electrochemical activity at biological interfaces of single entities. Utilizing various SEPM probe manipulations allows real-time monitoring of the morphology and physiological activities of single biological entities, offering vital electrochemical insights into biological processes. This review focuses on the application of five SEPM techniques in imaging single biological entities, highlighting their unique advantages in the observation and quantitative evaluation of biological morphology.
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