Diagnosis and Management of Malignant Epithelial Nail Unit Tumors.

Diagnostics (Basel)

Dermatology Department, Saint Pierre and Brugmann University Hospitals, Université Libre de Bruxelles, 1000 Brussels, Belgium.

Published: October 2024

AI Article Synopsis

  • Malignant tumors of the nail unit, like squamous cell carcinoma and basal cell carcinoma, can be hard to diagnose because they often look like benign issues, making early detection important.
  • * This review examines various types of malignancies affecting the nail unit, discussing their clinical features, pathology, and surgical management challenges.
  • * Proper evaluation and treatment strategies are critical for improving patient outcomes and preserving nail function during surgery.*

Article Abstract

: Malignant epithelial nail unit tumors pose significant diagnostic and therapeutic challenges due to their clinical presentation often mimicking benign conditions and due to the need to preserve as much nail unit function as possible during surgery. Early detection is crucial, even if none of these tumors represent a life-threatening disease. : This review focus on squamous cell carcinoma, verrucous carcinoma, eccrine porocarcinoma, onychocytic carcinoma, basal cell carcinoma, malignant onychopapilloma, malignant onycholemmal cyst and onycholemmal carcinoma. : Existing literature on the aforementioned tumors has been revised and synthesized. : Clinical presentation, pathology, diagnostic procedures, risk factors and the challenges associated with surgical management have been described in detail. : Malignant epithelial tumors of the nail unit require careful evaluation and management due to their complex presentation. Early detection and an informed surgical approach are essential to improve patient outcomes and minimize complications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11545385PMC
http://dx.doi.org/10.3390/diagnostics14212379DOI Listing

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