: Biochemical recurrence (BCR) after radical prostatectomy (RP) is a significant predictor of distal metastases and mortality in prostate cancer (PCa) patients. This systematic review aims to evaluate the accuracy of artificial intelligence (AI) in predicting BCR post-RP. : Adhering to PRISMA guidelines, a comprehensive literature search was conducted across Medline, Embase, Web of Science, and IEEE Xplore. Studies were included if they utilised AI to predict BCR in patients post-RP. Studies involving patients who underwent radiotherapy or salvage RP were excluded. This systematic review was registered on PROSPERO (International prospective register of systematic reviews) under the ID CRD42023482392. : After screening 9764 articles, 24 met the inclusion criteria. The included studies involved 27,216 patients, of whom 7267 developed BCR. AI algorithms developed using radiological parameters demonstrated higher predictive accuracy (median AUROC of 0.90) compared to algorithms based solely on pathological variables (median AUROC of 0.74) or clinicopathological variables (median AUROC of 0.81). According to the Prediction Model Risk of Bias Assessment Tool (PROBAST), the overall risk of bias was unclear in three studies due to ambiguous inclusion criteria and the exclusion of many patients because of missing follow-up data. In seven studies, the developed AI outperformed or was at least equivocal to traditional methods of BCR prediction. : AI shows promise in predicting BCR post-RP, particularly when radiological data were used in its development. However, the significant variability in AI performance and study methodologies highlights the need for larger, standardised prospective studies with external validation prior to clinical application.
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http://dx.doi.org/10.3390/cancers16213596 | DOI Listing |
JPEN J Parenter Enteral Nutr
December 2024
Edge Hill University, Ormskirk, UK.
Survivorship after pediatric critical illness is high in developed countries, but many suffer physical morbidities afterwards. The increasing focus on follow-up after critical illness has led to more pediatric studies reporting muscle mass changes (using ultrasound), albeit with different results. A systematic literature review was undertaken examining muscle mass changes, assessed by ultrasound of the quadriceps femoris muscle in children who are critically ill.
View Article and Find Full Text PDFTrauma Violence Abuse
December 2024
Department of Psychology, Çankaya University, Ankara, Turkey.
The ongoing conflicts in the Middle East have led to a substantial influx of Syrian refugees, exposing them to severe traumatic experiences and contributing to a range of mental health issues. This systematic review examines psychotherapeutic interventions employed in psychological treatment studies with Syrian refugees, focusing on 22 articles identified across Scopus, PubMed, Web of Science, and ScienceDirect. The review highlights the need for psychotherapeutic intervention for Syrian refugees due to the high prevalence of post-traumatic stress, depression, anxiety, grief, and loss which results from an increased risk of various forms of violence and exploitation.
View Article and Find Full Text PDFTher Adv Respir Dis
December 2024
Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background: Muscular atrophy often can be seen at the end of stage in many chronic diseases. It will also negatively influence patients' outcomes. Different studies showed that the association between muscular atrophy and mortality in patients with chronic obstructive pulmonary disease (COPD) was unclear.
View Article and Find Full Text PDFOrthod Craniofac Res
December 2024
Department of Orthodontics and Dentofacial Orthopedics, Dental School/Medical Faculty, University of Bern, Bern, Switzerland.
The primary objective was to systematically assess the prevalence, incidence and risk factors of WSLs with orthodontic treatment. The secondary objective was to compare the prevalence of WSLs between conventional fixed appliances (CFA) and other appliances, as well as with no treatment. PubMed, Scopus, Web of Science, LILACs, Virtual Health Library and Cochrane CENTRAL were searched.
View Article and Find Full Text PDFThis review aims to contribute to the understanding of violence against women and girls in conflict-affected and fragile settings through a systematic review and meta-analysis to document the available evidence on the prevalence of intimate partner violence and non-partner sexual violence during periods of armed conflict and in post-conflict periods. A total of 45 studies were included. Inclusion criteria were: population-based, observational studies that collected quantitative data with women (aged 15 years or older), included prevalence data on intimate partner violence or sexual violence, was collected in a conflict-affected context (active conflict or within 10 years after conflict) and was self-reported by women themselves.
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