Effective detection techniques are important for wildlife monitoring and conservation applications and are especially helpful for species that live in complex environments, such as arboreal animals like koalas (). The implementation of infrared cameras and drones has demonstrated encouraging outcomes, regardless of whether the detection was performed by human observers or automated algorithms. In the case of koala detection in eucalyptus plantations, there is a risk to spotters during forestry operations. In addition, fatigue and tedium associated with the difficult and repetitive task of checking every tree means automated detection options are particularly desirable. However, obtaining high detection rates with minimal false alarms remains a challenging task, particularly when there is low contrast between the animals and their surroundings. Koalas are also small and often partially or fully occluded by canopy, tree stems, or branches, or the background is highly complex. Biologically inspired vision systems are known for their superior ability in suppressing clutter and enhancing the contrast of dim objects of interest against their surroundings. This paper introduces a biologically inspired detection algorithm to locate koalas in eucalyptus plantations and evaluates its performance against ten other detection techniques, including both image processing and neural-network-based approaches. The nature of koala occlusion by canopy cover in these plantations was also examined using a combination of simulated and real data. The results show that the biologically inspired approach significantly outperformed the competing neural-network- and computer-vision-based approaches by over 27%. The analysis of simulated and real data shows that koala occlusion by tree stems and canopy can have a significant impact on the potential detection of koalas, with koalas being fully occluded in up to 40% of images in which koalas were known to be present. Our analysis shows the koala's heat signature is more likely to be occluded when it is close to the centre of the image (i.e., it is directly under a drone) and less likely to be occluded off the zenith. This has implications for flight considerations. This paper also describes a new accurate ground-truth dataset of aerial high-dynamic-range infrared imagery containing instances of koala heat signatures. This dataset is made publicly available to support the research community.
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http://dx.doi.org/10.3390/s24217048 | DOI Listing |
Bioeng Transl Med
January 2025
Research Institute of Transplant Medicine, Tianjin First Central Hospital, School of Medicine, Nankai University Tianjin China.
Pump is a vital component for expelling the perfusate in small animal isolated organ normothermic machine perfusion (NMP) systems whose flexible structure and rhythmic contraction play a crucial role in maintaining perfusion system homeostasis. However, the continuous extrusion forming with the rigid stationary shaft of the peristaltic pumps can damage cells, leading to metabolic disorders and eventual dysfunction of transplanted organs. Here, we developed a novel biomimetic blood-gas system (BBGs) for preventing cell damage.
View Article and Find Full Text PDFCell therapies are at the forefront of novel therapeutics. Neutrophils, despite being the most populous immune cells in human blood circulation, are not considered a viable option for cellular therapies because of their short lifespan and poor understanding of their role in the pathophysiology of various diseases. In inflammatory conditions, neutrophils exhibit an activated phenotype.
View Article and Find Full Text PDFBioeng Transl Med
January 2025
Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University Boston Massachusetts USA.
Immune checkpoint inhibitors (ICIs) represent new therapeutic candidates against glioblastoma multiforme (GBM); however, their efficacy is clinically limited due to both local and systemic immunosuppressive environments. Hence, therapeutic approaches that stimulate local and systemic immune environments can improve the efficacy of ICIs. Here, we report an adoptive cell therapy employing neutrophils (NE) that are activated via surface attachment of drug-free disk-shaped backpacks, termed Cyto-Adhesive Micro-Patches (CAMPs) for treating GBM.
View Article and Find Full Text PDFACS Nano
January 2025
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China, Hefei, Anhui 230027, PR China.
Flexible on-skin electronics present tremendous popularity in intelligent electronic skins (e-skins), healthcare monitoring, and human-machine interfaces. However, the reported e-skins can hardly provide high permeability, good stretchability, and large sensitivity and are limited in long-term stability and efficient recyclability when worn on the human body. Herein, inspired from the human skin, a permeable, stretchable, and recyclable cellulose aerogel-based electronic system is developed by sandwiching a screen-printed silver sensing layer between a biocompatible CNF/HPC/PVA (cellulose nanofiber/hydroxypropyl cellulose/poly(vinyl alcohol)) aerogel hypodermis layer and a permeable polyurethane layer as the epidermis layer.
View Article and Find Full Text PDFAnal Chim Acta
February 2025
Department of Clinical Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China; Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, Hangzhou, 310003, China. Electronic address:
Background: Amplified imaging of microRNA (miRNA) in cancer cells is essential for understanding of the underlying pathological process. Synthetic catalytic DNA circuits represent pivotal tools for miRNA imaging. However, most existing catalytic DNA circuits can not achieve the reactant recycling operation in cells and in vivo.
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