AI Article Synopsis
- - This review focused on enhancing commercial soft lining materials (SLMs) by incorporating different antifungal agents, such as polyene antibiotics, azole drugs, and antiseptics, to improve their properties.
- - It examined how these modifications affected physical characteristics of SLMs, including factors like drug release, water absorption, and strength.
- - The findings provide valuable insights for prosthetic dentistry, particularly in addressing candidiasis, a common issue for denture users.
Article Abstract
This review examined the current state of knowledge on the modifications of commercial soft lining materials (SLMs) with a variety of antifungal compounds: (i) polyene antibiotics, including nystatin and amphotericin B, (ii) azole drugs, including fluconazole, itraconazole, clotrimazole, ketoconazole, and miconazole, and (iii) antiseptics, including chlorhexidine salts to give them anti- properties. The effect of such modifications on the SLMs' physical properties, such as drug release, water sorption, surface properties, bond strength, tensile strength, and hardness, was also analyzed. In effect, this study provided a unique compilation of research results obtained for numerous properties of SLM modified with antifungal compounds that differ in their chemical structure and mechanism of antifungal action. These results might also be useful for prosthetic dentistry, where SLMs are used to prevent and treat candidiasis, the most common disease among denture wearers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547545 | PMC |
| http://dx.doi.org/10.3390/ma17215383 | DOI Listing |
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