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Correction: Hemoptysis due to ruptured lung abscess successfully treated by exploratory thoracoscopy: report of a case.
Gen Thorac Cardiovasc Surg Cases
November 2023
Department of Thoracic Surgery, Tokyo Women's Medical University, Kawada-Cho 8-1, Shinjuku-Ku, Tokyo, 162-8666, Japan.
The Hidden Culprit: A Computed Tomography Diagnosis of H-Type Tracheoesophageal Fistula in an Adult Revealed After Two Decades of Pulmonary Infections.
Cureus
October 2024
Radiology, Souss Massa University Hospital, Agadir, MAR.
Article Synopsis
- A 41-year-old male with a history of cardiopathy and respiratory issues presented with severe symptoms related to heart failure, including significant dyspnea and edema after years of recurrent infections.
- Diagnostic tests revealed multiple complications including dilation of cardiac chambers and a rare congenital condition known as H-type tracheoesophageal fistula (TEF), which contributed to his respiratory problems.
- The patient was admitted to the ICU for intensive management, including treatment for pulmonary artery hypertension and preparation for surgical intervention to repair the fistula.
Background: MK-5475 is an investigational inhaled soluble guanylate cyclase stimulator hypothesised to avoid most side-effects of systemic vasodilation.
Methods: The phase 2 INSIGNIA-PAH (NCT04732221) trial randomised adults with pulmonary arterial hypertension (PAH) on stable background therapy 1:1:1:1 to once-daily dosing with placebo, MK-5475 32 µg, 100 µg or 380 µg dry powder inhalation for 12 weeks.
Objectives: The objectives were to evaluate pulmonary vascular resistance (PVR; primary), 6-min walk distance (6MWD; secondary), additional selected haemodynamic parameters, and safety and tolerability in participants with PAH.
Severe Coagulopathy and Intra-Alveolar Haemorrhage Due to Fat Malabsorption in Celiac Disease.
Eur J Case Rep Intern Med
September 2024
Nephrology and Hypertension Department, Samson Assuta Ashdod University Hospital, Ashdod, Israel.
Article Synopsis
- Celiac disease can manifest with unusual symptoms like fat malabsorption and coagulopathy, demonstrated by a 64-year-old patient with severe anemia and an elevated INR due to vitamin K deficiency.
- Despite initial treatments, the patient's condition worsened, revealing that celiac disease was behind the coagulopathy and subsequent bleeding.
- Treatment with a gluten-free diet and vitamin supplementation effectively resolved the patient’s symptoms and coagulation issues, underscoring the need to consider celiac disease in unexplained bleeding disorders.
A Persistent Pulmonary Puzzle: Diagnosing Hodgkin Lymphoma in a Young Female With Chronic Respiratory Symptoms.
Cureus
July 2024
Department of Internal Medicine, Tubas Turkish Governmental Hospital, Tubas, PSE.
Hodgkin lymphoma (HL), a lymphoid neoplasm characterized by the presence of Reed-Sternberg cells, often presents with painless lymphadenopathy and systemic symptoms. This case report details the diagnostic journey of a 27-year-old non-smoker female with chronic respiratory symptoms, including persistent cough, hemoptysis, and weight loss over two years. Despite multiple treatments for presumed infections and extensive diagnostic procedures, the correct diagnosis of HL was delayed due to atypical pulmonary manifestations, notably necrotizing pneumonia and multiple cavitary lung lesions.
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