Understanding the dynamics of the African swine fever virus during periods of intense replication is critical for effective combatting of the rapid spread. In our research, we have developed a fractional-order SVEIR model using the Caputo derivatives to investigate this behaviour. We have established the existence and uniqueness of the solution through fixed point theory and determined the basic reproduction number using the next-generation matrix method. Our study also involves an examination of the local and global stability of disease-free equilibrium points. Additionally, we have conducted optimal control analysis with two control variables to increase the number of recovered pigs while reducing the number of those infected and exposed. We have supported our findings with numerical simulations to demonstrate the effectiveness of the control strategy.
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http://dx.doi.org/10.1038/s41598-024-78140-9 | DOI Listing |
Sci Rep
November 2024
Department of Applied Sciences, National Institute of Technology Goa, Kottamoll Plateau, Cuncolim, Goa, 403703, India.
Understanding the dynamics of the African swine fever virus during periods of intense replication is critical for effective combatting of the rapid spread. In our research, we have developed a fractional-order SVEIR model using the Caputo derivatives to investigate this behaviour. We have established the existence and uniqueness of the solution through fixed point theory and determined the basic reproduction number using the next-generation matrix method.
View Article and Find Full Text PDFInfect Dis Model
March 2025
Jinzhou Center for Disease Control and Prevention, Jinzhou, 121000, Liaoning, China.
As of May 2024, the main strains of COVID-19 caused hundreds of millions of infection cases and millions of deaths worldwide. In this study, we consider the COVID-19 epidemics with the main strains in the Chinese mainland. We study complex interactions among hosts, non-pharmaceutical interventions, and vaccinations for the main strains by a differential equation model called SVEIR.
View Article and Find Full Text PDFJ Math Biol
July 2024
School of Mathematics and Physics, Lanzhou Jiaotong University, Lanzhou, 730070, Gansu, People's Republic of China.
The efficacy of vaccination, incomplete treatment and disease relapse are critical challenges that must be faced to prevent and control the spread of infectious diseases. Age heterogeneity is also a crucial factor for this study. In this paper, we investigate a new age-structured SVEIR epidemic model with the nonlinear incidence rate, waning immunity, incomplete treatment and relapse.
View Article and Find Full Text PDFInfect Dis Model
September 2024
Jinzhou Center for Disease Control and Prevention, Jinzhou, 121000, Liaoning, China.
The complex interactions were performed among non-pharmaceutical interventions, vaccinations, and hosts for all epidemics in mainland China during the spread of COVID-19. Specially, the small-scale epidemic in the city described by SVEIR model was less found in the current studies. The SVEIR model with control was established to analyze the dynamical and epidemiological features of two epidemics in Jinzhou City led by Omicron variants before and after Twenty Measures.
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