Objectives: Slightly acidic electrolyzed water (SAEW) is produced by electrolyzing 2-6% diluted hydrochloric acid in a membrane-less chamber, resulting in 5.0-6.5 pH, and can be applied to various foods as a disinfectant. Although SAEW has shown to have bactericidal activity, the details of its anti-fungal effects towards Candida species remain unknown. Therefore, we examined the fungicidal effects of SAEW on Candida spp. and biofilms on acrylic resins.
Methods: The fungicidal effects of SAEW on Candida spp. at different reaction times and total numbers of colonies in culture plates were examined. Subsequently, SAEW was added to Candida spp. biofilms formed on polystyrene plates, and adenosine triphosphate (ATP) in SAEW was measured to examine its fungicidal effects towards Candida spp. biofilms. The fungicidal effect of SAEW on Candida spp. biofilms was determined by counting the number of colonies on the acrylic resin after adding SAEW.
Results: SAEW completely killing activity within 1 min with the tested Candida spp.. C. albicans and C. glabrata ATP were increased 5 min after adding SAEW compared with the controls, suggesting the removal of biofilm. Of the C. albicans on acrylic resin, > 99.9%were killed by SAEW compared to their levels in deionized distilled water (DW) (76.2x10/mL and 43.3x10/mL, respectively). Similarly, 93.1% of C. glabrata were killed by SAEW compared to DW (159.3x102/mL).
Conclusions: SAEW may be useful in preventing oral candidiasis as part of oral care.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.job.2024.10.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring oral candidiasis among cancer patients undergoing chemotherapy in eastern Iran.
Iran J Microbiol
December 2024
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Background And Objectives: Understanding the epidemiology of species among cancer patients is crucial for preventing invasive infections. This study aimed to identify species and assess risk factors among cancer patients receiving chemotherapy in Birjand, eastern Iran.
Materials And Methods: The samples were obtained from the oral cavity of 140 patients and the initial identification of species was carried out through fungal cultures.
Antibiofilm Activity of Epinecidin-1 and Its Variants Against Drug-Resistant and Isolates from Vaginal Candidiasis Patients.
Infect Dis Rep
December 2024
Microbial Biotechnology Laboratory, Department of Marine Biotechnology, Bharathidasan University, Tiruchirappalli 620024, India.
Indwelling intrauterine contraceptive devices (IUDs) have surfaces that facilitate the attachment of spp., creating a suitable environment for biofilm formation. Due to this, vulvovaginal candidiasis (VVC) is frequently linked to IUD usage, necessitating the prompt removal of these devices for effective treatment.
View Article and Find Full Text PDFAntifungal susceptibility profile of Candida species and uncommon yeasts from drug abusers with oral candidiasis.
BMC Oral Health
December 2024
Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
In Iran, there is limited information regarding the species distribution and antifungal susceptibility profiles of yeast isolates from drug addicts suffering from oral candidiasis (OC). In this study, 104 yeast isolates, including 98 Candida species and 6 uncommon yeasts, were collected from 71 drug abusers with OC. The susceptibility profiles of Candida spp.
View Article and Find Full Text PDFSubsequent bacteremia associated with intravascular catheter colonization with Staphylococcus aureus, Gram-negative rods, and Candida species in children.
J Infect Chemother
December 2024
Center for Postgraduate Education and Training, National Center for Child Health and Development, Tokyo, Japan.
Subsequent bacteremia developed in 14% of patients with positive catheter tip cultures but concurrent negative blood cultures. The occurrence of subsequent bacteremia did not differ significantly by pathogens (Staphylococcus aureus, Gram-negative rods [GNR], and Candida spp.).
View Article and Find Full Text PDFPrevalence of fungal colonization among patients with psoriasis in difficult-to-treat areas: impact of apremilast on mycotic burden and clinical outcomes.
Front Immunol
December 2024
Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
Introduction: Fungi, including , may be a trigger or exacerbate psoriasis, especially in difficult to treat (DTT) areas, through the activation of IL-17/23 axis.
Methods: In this study, seventy patients with DDT psoriasis were enrolled to evaluate species and/or other opportunistic fungi colonization rate at baseline (T0) and the impact of apremilast on fungal load, clinical outcome, serum cytokine levels and biochemical serum profile of patients after 16, 24 and 52 weeks of treatment.
Results: In our population, 33 (47%) patients were colonized by spp.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!