Non-coding RNAs affect carcinogenic processes in diverse tissues, such as prostate. Several of these transcripts act as oncogenes driving prostate cancer. Thus, they are putative targets for treatment of this type of cancer. CRISPR/Cas9 technology has provided new tools for modulation of expression of these oncogenes in order to combat several aspects of carcinogenesis, including invasion cascades and metastasis. This review aimed to describe novel achievements in modulation of expression of non-coding RNAs using CRISPR/Cas9 technology in prostate cancer.
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| http://dx.doi.org/10.1016/j.prp.2024.155710 | DOI Listing |
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