Self-retained, cryopreserved amniotic membrane for a scleral defect caused by mitomycin C: A case report.

Purpose: To report a case of scleral melting noted within weeks after symblepharon release and pterygium excision with peri-operative adjuvant topical Mitomycin C (MMC) that was salvaged with in-office cryopreserved membrane.

Observations: A 61-year-old Hispanic gentleman with history of pterygium excision many years prior underwent right nasal pterygium excision and symblepharon release using bare sclera technique followed by topical MMC 0.1 % for a week, 16 years ago. He was noted to have a right nasal scleral thinning. He was successfully treated conservatively with in-office cryopreserved amniotic membrane without further progression of the scleral melting or surgical intervention required.

Conclusions And Importance: Short-term complication of pterygium excision with adjuvant topical MMC may occur. This case shows that early detection and recognition of the complication can be sight-saving with in-office cryopreserved amniotic membrane.