Inclusiveness of the All of Us Research Program improves polygenic risk scores and fosters genomic medicine for all.

Commun Med (Lond)

Department of Immunology and Molecular Biology, College of Health Sciences, School of Biomedical Sciences, Makerere University, Kampala, Uganda.

Published: November 2024

Polygenic risk scores (PRS) show promise but have accuracy disparities across ancestries due to underrepresentation in the existing genomic databases. Here, we outline the initiative of All of Us Research Program in refining PRS and advancing genomic medicine for all.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11544250PMC
http://dx.doi.org/10.1038/s43856-024-00647-zDOI Listing

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