Is cardiovascular disease in PCOS driven by MASLD?

Trends Endocrinol Metab

Department of Internal Medicine, Division of Endocrinology and Metabolic Diseases, Maastricht University Medical Center, Maastricht, The Netherlands; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands. Electronic address:

Published: November 2024

AI Article Synopsis

  • * These findings suggest new ways to prevent and treat PCOS and cardiovascular issues, both medically and in broader society.
  • * The research highlights the importance of understanding lipid accumulation for developing effective health strategies.

Article Abstract

Recent genetic studies have implicated an active role for intrahepatic lipid accumulation in the pathogenesis of both polycystic ovary syndrome (PCOS) and cardiovascular disease. These new insights may provide novel (non)pharmacological opportunities for the prevention and treatment of PCOS and cardiovascular disease at both the societal and clinical level.

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Source
http://dx.doi.org/10.1016/j.tem.2024.10.005DOI Listing

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